Distribution and clinical significance of HBV genotypes in Lanzhou district

Qin Hua; Wu XiaoQing

Issue 3

Mar. 2010

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Article Navigation > Journal of Clinical Hepatology > 2010 > 26(3): 295-296

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Distribution and clinical significance of HBV genotypes in Lanzhou district

Published Date: 2010-03-20

Abstract

Abstract

Objective To study the distribution and clinical significance of Hepatitis B Virus (HBV) genotypes in Lanzhou district. Methods HBV genotype was tested in 163 patients by real-time PCR.Results HBV genotype C (92.02%) was a found to be the major genotype in Lanzhou district. Genotype C and combined genotypes B and C accounted for 4.30% and 3.68%, respectively. Cirrhosis was higher in patients with genotype C than genotype B patients (49.33%vs34.00%) , but the difference was not statistically significant. Furthermore, cirrhosis and liver cancer patients were older than patients with chronic hepatitis B and the HBVDNA level was lower in chronic hepatitis B patients.Conclusion HBV genotype C is the major genotypes in Lanzhou district. Besides HBV genotype, factors such as age, disease course and the HBV DNA levels are important factors in disease prognosis.
- hepatitis B virus,
- hepatitis B,
- genotype,
- polymerase chain reaction

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通讯作者: 陈斌, bchen63@163.com

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沈阳化工大学材料科学与工程学院沈阳 110142

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Distribution and clinical significance of HBV genotypes in Lanzhou district

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Distribution and clinical significance of HBV genotypes in Lanzhou district

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