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ISSN 1001-5256 (Print)
ISSN 2097-3497 (Online)
CN 22-1108/R
Issue 12
Dec.  2011
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Clinical characteristics and distribution of hepatitis B virus genotypes in CHB patients in Yantai area

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  • Published Date: 2011-12-20
  • Objective To investigate the clinical characteristics and distribution of hepatitis B virus (HBV) genotypes in Yantai city.Methods HBV genotypes were detected in 362 patients with chronic HBV infection using Real-time PCR.Results HBV genotype B, C and non-B or non-C were identified in 7 (1.9%) , 344 (95.0%) and 11 (3.0%) patients respectively.The age of patients infected with HBV genotype B, C and non-B or non-C is 36.29±17.54, 37±10.64 and 45.09±10.67 respectively (P=0.050) .No significant difference was found in the positive rate of HBeAg or the serum level of ALT, HBV DNA among the patients with genotype B, C and non-B or non-C (P>0.005) .Conclusion Genotype B, C and non-B or non-C have been found in the CHB patients of Yantai city and genotype C is the predominant genotype found.There maybe significant difference among the ages of patients infected with different HBV genotypes.

     

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