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Feb.  2008
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Article Navigation >  Journal of Clinical Hepatology  > 2008  >  24(2): 106-108

c-myb在肝细胞癌组织中的表达及临床意义

  • Published Date: 2008-02-20
    Abstract
  • Objective To study the expression of c-myb in human hepatocelluar carcinoma tissues, we explored its role in the occurrence and development of HCC and clinical significance.Methods The protein expressions of c-myb were detected in 55 HCC tissues, 55 peri-carcinoma tissues, 12 hepatic cirrhosis tissues and 11 normal liver tissues by immunohistochemistry.Results The expression of c-myb protein in HCC tissues compared with normal liver tissues, its expression in peri-carcinoma tissues compared with hepatic cirrhosis tissues were significantly higher (P=0.000) .Conclusion These suggested that overexpression of c-myb gene might be an early accidence in the pathogenesis of HCC, and might play an important role in the occurrence and development of HCC, detecting the expression of c-myb had clinical significance.

     

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    • References(9)
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