脂肪肝患者血清瘦素水平测定及与胰岛素抵抗关系的探讨

Objective To investigate the clinical significance of the levels of serum leptin in fatty liver patients.Methods Patients with fatty liver were admitted to the investigations, The blood glucose、liver function、blood grease、insulin、and leptin were detectcted.The candidates height and weight were measured respectively;body mass index and percent body fat were calculated.The level of leptin was measured by ELISA, Insulin resistance was showed by HOMAIR.The serum leptin level from the test group was compared with that from the control group.Result The level of leptin in fatty liver increased obviously than that of the controls;The serum leptin in fatty liver is relevant to BMI, ALT, CHE, and it have no relationships with insulin resistance.Conclusion The serum leptin in fatty liver is one of the danger factors which correlates with the disease itself, but it has no direct relevance to insulin resistance.