非酒精性脂肪肝与胰岛素抵抗的关系

To study the relationship between non-alcoholic fatty liver disease and insulin resistance.63 non-alcoholic fatty liver disease patients (male 35, femal 28) and 20 obesity without fatty liver disease were selected.Fasting serum insulin levels was measured by radio-immunoassay, insulin resistance index was estimated by the homeostasis model assessment (HOMA-IR) .Compared to controlgroup, patients with non-alcoholic fatty liver disease were characterized by hyperinsluinemia, elevated insulin resistance index (P<0.01) .Serum insulin and insulin resistance index were higher in heavy fatty liver disease patients than medium and light patients (P<0.05) .In the pathogeneses of non-alcoholic fatty liver disease, insulin resistance was an original factor probably and not a following changing.