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ISSN 1001-5256 (Print)
ISSN 2097-3497 (Online)
CN 22-1108/R
Issue 8
Aug.  2011
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Circulating tumor cells of hepatocellular carcinoma and their clinical implications

  • Published Date: 2011-08-20
  • Primary hepatocellular carcinoma (HCC) often invades into vessels and has a distal metastasis at an early stage, which have less curable options and a poor prognosis.The metastasis can be found early by identification and isolation of circulating tumor cells (CTC) in the bloodstream.Therefore, the detection of CTC in patients with HCC is beneficial to evaluate the curative effect and block the metastasis, despite the fact that the markers used for the detection of CTC (such as EpCAM and AFP etal) are overlapped with those for cancer stem cells (CSC) .Moreover, CTC number is small in the bloodstream, thus, more sensitive and specific markers and techniques to test the CTC are needed to detect and isolate these cells.

     

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