A possible receptor for beta-2-glycoprotein I on the membrane of hepatoma cell line SMMC-7721

Gao YanHang; Gao PuJun; Wang Dan; Shi Yang; Po YunFeng; Yang HanYi

Issue 3

Mar. 2006

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Article Navigation > Journal of Clinical Hepatology > 2006 > 22(3): 209-211

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SMMC-7721肝癌细胞膜上β2糖蛋白I可能的受体

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Published Date: 2006-03-20

Abstract

Abstract

To study the interaction of beta-2-glycoprotein I (β2GPI) with hepatocye, and further to explore whether β2GPI play an important role in hepatitis B virus (HBV) infection.Using Ligand blot technique, we detected the interaction of β2GPI with the hepatoma cell line SMMC-7721, the gastric carcinoma cell line SGC-7901 and the lymphoma cell line HL-60.A specific 40kD β2GPI band was observed in the case of SMMC-7721.No such band was observed in HL-60 and SGC-7901.There is the specific β2GPI binding protein in SMMC-7721.This protein maybe participates in HBV infection.
- beta-2-glycoprotein I,
- hepatoma cell line SMMC-7721,
- receptor,
- hepatitis B virus

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通讯作者: 陈斌, bchen63@163.com

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沈阳化工大学材料科学与工程学院沈阳 110142

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SMMC-7721肝癌细胞膜上β2糖蛋白I可能的受体

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SMMC-7721肝癌细胞膜上β2糖蛋白I可能的受体

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