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ISSN 1001-5256 (Print)
ISSN 2097-3497 (Online)
CN 22-1108/R
Issue 2
Feb.  2000
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刺五加皂甙对肝癌细胞凋亡的影响

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  • Published Date: 2000-02-20
  • WT5”BZ]To detect Acanthopanax senticosus (ASS) induce apoptosis of hepatocellular carcinoma (HCC) cells, the morphologic changes and DNA fragmentation of HCC cells induced by ASS were observed with transmission electron microscope and agarose gel electrophoresis assays The results showed that under electron microscope, it was observed ASS lead to HCC cells apoptosis DNA ladder fragmentations changes induced by ASS were clearly and the changes become significant with dosage increase of ASS It suggestes that ASS induce apoptosis of HCC cells [WT5”HZ]

     

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  • 〔1〕金有景 抗癌食药 , 中国食品出版社出版 , 1989, 2 44
    〔2〕WangJIImmunomodudularyactivityofpatysacharidefromAcanthopanaxobvatusroots, plantaMedicine, 1991∶5 7 ( 4 ) ∶3 3 5
    []〔3〕张文智 , 张乃哲 , 陈秀鉴 刺五加多糖和GST对实验性肝癌影响的病理学研究 肿瘤防治研究  1997, 2 4 ( 2 ) ∶78-80
    〔4〕阳健主编 中药现代研究与临床应用 第一版 , 北京学苑出版社  1994, 411
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      沈阳化工大学材料科学与工程学院 沈阳 110142

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