Study on Octreotide Induce apoptosis of Human Hepatocelluler Carcinoma Cells

Shi Yang; Po YunFeng; Zhang MingLei

Issue 3

Mar. 2001

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Article Navigation > Journal of Clinical Hepatology > 2001 > 17(3): 182-183

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奥曲肽诱导人肝癌细胞凋亡的研究

Published Date: 2001-03-20

Abstract

Abstract

To study Octreotide inducing apoptosis of hepatocellular carcinoma (HCC) cells, the morphologic changes and the expression of Caspase 3 were observed with light, electron microscope and Western blot assay.It showed that Octreotide could induce condensation of nuclear, vacuolar degeneration of mitochondria, reduction of microvillus, and so on.We can also conclude that Octreotide can strengthen the expression of Caspase 3 and activiate it so that inducing apoptosis of HCC cells.
- Octreotide,
- Hepatocellular carcinoma cells,
- Caspase 3,
- Apoptosis

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通讯作者: 陈斌, bchen63@163.com

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沈阳化工大学材料科学与工程学院沈阳 110142

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奥曲肽诱导人肝癌细胞凋亡的研究

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奥曲肽诱导人肝癌细胞凋亡的研究

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