兰州地区TTV感染的血清学及临床研究

WT5”BZ]To study the infections rate and pathogenicity of transfusion transmitted Virus (TTV) among blood donors, intravenous drug abusers and patients with liver disease in Lanzhou TTV DNA from sera of blood donors intraverous drug abusers and patients with liver disease were detected by nested PCR (n PCR) :TTV DNA was detected in 9/120 (7 5%) sera of blood donors, in 15/56 (26 8%) sera of intravenous drug abusers and in 10/74 (13 4%) sera of patients with liver disease Among 10 TTV infected patients, there were 6 patients with Simple TTV infection, 4 cases were associated with elevated aminotransferase, 3 cases were AIH :The result indicated TTV that infection can be transmitted by blood and gastrointestinal but the pacthogenicity is mild Further study should be done to explore its eitiology epidmiology and clinical significance [WT5”HZ]