[1]Pachiadakis I, Pollara G, Chain BM, et al.Is hepatitis C virus infection of dendritic cells a mechanism facilitating viral persistence[J].Lancet Infect Dis, 2005, 5 (5) :296-304.
|
[2]Groux H, Foumier N, Cottrez F.Role of dendritic cells in the generation of regulatory T cells[J].Semin Immunol, 2004, 6 (2) :99-106.
|
[3]Onishi Y, Fehervari Z, Yamaguchi T, et al.Foxp3+natural resulatery T cells pmferentially form aggregates on dendritic cells in vitro and actively inhibit their maturation[J].Proc Natl Acad Sci, 2008, 105 (29) :10113-10118.
|
[4]Kanto T, Hayashi N, Takehara T, et al.Impaired allostimulatory capacity of peripheral blood dendritic cells recovered from hepatitis C virus-infected individuals[J].J Immunol, 1999, 162 (9) :5584-5591.
|
[5]Li W, Krishnadas DK, Kumar R, et al.Priming and stimulation of hepatitis C virus-specific CD4+and CD8+T cells against HCV antigens NS4, NS5a or NS5b from HCV-naive individuals:implications for prophylactic vaccine[J].Int Immunol, 2008, 20 (1) :89-104.
|
[6]Amjad M, Abdel-Haq N, Faisal M, et al.Decreased interferon-alpha production and impaired regulatory function of plasmacytoid dendritic cells induced by the hepatitis C virus NS 5 protein[J].Microbiol Immunol, 2008, 52 (10) :499-507.
|
[7]Bain C, Fatmi A, Zoulim F, et al.Impaired allostimulatory function of dendritic cells in chronic hepatitis C infection[J].Gastroenterology, 2001, 120 (33) :512-524.
|
[8]李军, 冯志华, 聂青和, 等.人DC-SIGN真核表达载体的构建及在K-562细胞中的表达[J].肝脏, 2006, 11 (1) :24-27.
|
[9]王敏, 王辉, 蒋小玲, 等.DC-SIGNR基因多态性与肝功能和HCV病毒载量的相关性[J].中国医师进修杂志, 2007, 30 (30) :3-5.
|
[10]Auffermann-Gretzinger S, Keeffe EB, Levy S.Impaired dendritic cell maturation in patients with chronic, but not resolved, hepatitis C virus infection[J].Blood, 2001, 97 (18) :3171-3176.
|
[11]Dolganiuc A, Kodys K, Kopasz A, et al.Hepatitis C virus core and nonstructural protein 3 proteins induce pro-and anti-inflammatory cytokines and inhibit tendritic cell differentiation[J].J Immunol, 2003, 170 (11) :5615-5624.
|
[12]Zimmermann M, Flechsig C, La Monica N, et al.Hepatitis C virus core protein impairs in vitro priming of specific T cell responses by dendritic cells and hepatocytes[J].J Hepatol, 2008, 48 (1) :51-60.
|
[13]Dolganiuc A, Paek E, Kodys K, et al.Myeloid den-dritic cells of patients with chronic HCV infection induce proliferation of regulatory T lymphocytes[J].Gastroenterology.2008, 135 (6) :2119-2127.
|
[14]Lai WK, Curbishley SM, Goddard S, et al.Hepatitis C is associated with perturbation of intrahepatic myeloid and plasmacytoid dendritic cell function[J].J Hepatol, 2007, 47 (3) :338-347.
|
[15]Klade CS, Wedemeyer H, Berg T, et al.Therapeutic vaccination of chronic hepatitis C nonresponder patients with the peptide vaccine IC41[J].Gastroenterology, 2008, 134 (5) :1385-1395.
|
[16]Firbas C, Boehm T, Buerger V, et al.Immunogenicity and safety of different injection routes and schedules of IC41, a Hepatitis C virus (HCV) peptide vaccine[J].Vaccine, 2010, 28 (12) :2397-2407.
|
[17]Chua BY, Eriksson EM, Brown LE, et al.A self-adj-uvanting lipopeptide-based vaccine candidate for the treatment of hepatitis C virus infection[J].Vaccine, 2008, 26 (37) :4866-4875.
|
[18]Gowans EJ, Roberts S, Jones K, et al.A phase I clinical trial of dendritic cell immunotherapy in HCV-infected individuals[J].J Hepatol, 2010, 53 (4) :599-607.
|
[19]Zabaleta A, Llopiz D, Arribillaga L, et al.Vaccination against hepatitis C virus with dendritic cells transduced with an adenovirus encoding NS3 protein[J].Mol Ther, 2008, 16 (1) :210-217.
|
[20]Yu H, Babiuk LA, van Drunen Littel-van den Hurk S.Strategies for loading dendritic cells with hepatitis C NS5a antigen and inducing protective immunity[J].J Viral Hepat, 2008, 15 (6) :459-470.
|
[21]Forde KA, Reddy KR.Hepatitis C virus infection and immunomodulatory therapies[J].Clin Liver Dis, 2009, 13 (3) :391-401.
|