Role of particulate matter 2.5 in the development and progression of liver cancer

Fei ZUO; Guodong LI; Ming LIU

doi:10.3969/j.issn.1001-5256.2022.04.038

Volume 38 Issue 4

Apr. 2022

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Abstract

References

Article Navigation > Journal of Clinical Hepatology > 2022 > 38(4): 927-930

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Role of particulate matter 2.5 in the development and progression of liver cancer

DOI: 10.3969/j.issn.1001-5256.2022.04.038

Fei ZUO¹,
Guodong LI²,
Ming LIU^{1
,
,
,}

1.
Department of General Surgery, The Second Affiliated Hospital of Harbin Medical University, Harbin 150001, China
2.
Department of General Surgery, The Fourth Affiliated Hospital of Harbin Medical University, Harbin 150001, China

Research funding:

Harbin Applied Technology Research and Development Project (Excellent Discipline Leader Class B) (2017RAXXJ057);

Natural Science Foundation of Heilongjiang Province-Joint Guidance Project (LH2020H066)

More Information

Corresponding author: LIU Ming, mliu35@aliyun.com(ORCID: 0000-0001-1640-5892)
Received Date: 2021-08-20
Accepted Date: 2021-10-08
Published Date: 2022-04-20

Abstract

Abstract

Particulate matter 2.5 (PM2.5), as one of the main components of atmospheric particulate matter, has become an important factor affecting people's health; however, there are relatively few studies on the association of PM2.5 with the development and progression of liver cancer. This article reviews the epidemiological study of PM2.5 and liver cancer, summarizes the mechanisms of PM2.5 causing liver cancer (including changing enzyme activity, affecting gene expression, inducing endoplasmic mesh stress, causing liver fat degeneration, and leading to liver fibrosis), and discusses the influence of PM2.5 exposure on the prognosis of liver cancer.
- Liver Neoplasms,
- Particulate Matter,
- Pathologic Processes,
- Prognosis

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References(38)

References

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