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ISSN 2097-3497 (Online)
CN 22-1108/R
Volume 40 Issue 8
Aug.  2024
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Article Navigation >  Journal of Clinical Hepatology  > 2024  >  40(8): 1525-1532

Phenotypic characteristics and toxicological mechanisms of herb-induced liver injury

DOI: 10.12449/JCH240804
  • 1.

    Senior Department of Hepatology，Department of Traditional Chinese Medicine，the Fifth Medical Center of PLA General Hospital，Beijing 100039，China

  • 2.

    School of Traditional Chinese Medicine，Capital Medical University，Beijing 100069，China

Research funding:

National Natural Science Foundation of China (82074112);

Innovation Team and Talents Cultivation Program of National Administration of Traditional Chinese Medicine (ZYYCXTD-C-202005);

the Joint Funds of the National Natural Science Foundation of China (U23A20519)

More Information
  • Corresponding author: WANG Jiabo， jiabo_wang@ccmu.edu.cn （ORCID： 0000-0002-1478-9693）
  • Received Date: 2024-05-06
  • Accepted Date: 2024-07-01
  • Published Date: 2024-08-25
    Abstract
  • In order to deal with the problem of the safety of Chinese herbal medicine in a scientific way and further meet the growing health needs of people， it is particularly important to deepen the research on herb-induced liver injury. This article elaborates on the phenotypic characteristics and toxicological mechanisms of herb-induced liver injury and emphasizes that it should not only rely on the previous knowledge of the toxicity of Chinese herbal medicine， but also understand the new types of idiosyncratic toxicity， indirect toxicity， and mixed toxicity， which provide a new perspective for understanding the toxicological mechanisms of herb-induced liver injury and are of great importance to investigate the phenotype and toxicological mechanism of herb-induced liver injury.

     

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    The first journal specializing in hepatobiliary and pancreatic diseases in China

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