Monitoring the change of interleukin-6 in the alcoholic liver disease and its clinical significance

Wang RuiKe; Liu XiuZhen; Zhang GuYun; Li Hong; Sun ZhaoCui; Zhang JinAn

Issue 2

Feb. 2005

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Article Navigation > Journal of Clinical Hepatology > 2005 > 21(2): 100-101

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酒精性肝病白细胞介素6的检测及意义

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Published Date: 2005-02-20

Abstract

Abstract

To study the relationship be tween the change of interleukin-6 (IL-6) activity and the level of hepatic fibro sis in alcoholic liver disease (ALD) .Among the 120 patients with ALD, the level o f interleukin-6 (IL-6) ?hyaluronic acid (HA) ?laminin (LN) , type Ⅲ procollagen ( PC-Ⅲ) and type Ⅳ collagen (Ⅳ-C) in serum is monitored.The same items are moni tored in the control group with 30 healthy people.The in acase of IL-6 in ALD gr oup (P<0.05～0.001) .The changes of HLIV?PC-Ⅲ and Ⅳ is marked nigher than the control group (P<0.001～0.0001) .The changes of IL-6 activity is Posilive correlaled with the level of hepatic fibrosis in ALD.
- alcoholic liver disease,
- in terleukin-6,
- hepatic fibrosis

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[1]梁扩寰肝脏病学[M].北京∶人民卫生出版社, 1995∶738

[2]森本道雄酒精性肝损害的最新研究进展[J].日本医学介绍, 1997, 72∶83

[3] GreventP , IraburuMJ, ReyesRoneroM , etat.Inductionofanaccutephaseinratsstimulatestheexperssionofal (I) porcollagenmessengerri bonucleicacidintheirlivers[J].LabInvest, 1995, 72∶83.

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通讯作者: 陈斌, bchen63@163.com

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沈阳化工大学材料科学与工程学院沈阳 110142

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酒精性肝病白细胞介素6的检测及意义

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酒精性肝病白细胞介素6的检测及意义

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