庚型肝炎病毒在慢性肝炎肝硬化中致病性及病理特征

WT5”BZ]To study the infection rate, the clinical and pathologic character of HG (Hepatitis G) , including chronic hepatitis and cirrhosis, We detected anti-HGV in serum by EIA and prepared McAb by HGV NS 5 to detect HGV in the hepatic tissues of 54 patients with chronic hepatitis and cirrhosis, also performed with SP immunohistochemical detection of HBsAg, HBcAg and HCVSN 3Ag in hepatic tissue of the patients HGV was found in 15 cases (27 8%) each one-third of which were respectively from 24 ligh mild degree, 16 medium degree and 14 cirrhosis patients (5/24, 5/16, 5/14) Mainly, Coinfection of HGV with HBV/HCV anounts to 80% but patients with HGV alone account for 20% HGV was found mainly in cytoplasm, some in cytonucleus sinultaneously or only in cytonucleus One case showed that HGAg was positive simply in Kuffer’s cell The patient with HGV alone gets sick in clinical concealment with prognosis favorable The coinfection of HGV with HBV/HCV may have significance for chronic hepatitis development [WT5”HZ]