非酒精性脂肪性肝病代谢组学与中医证候

高静静; 汪涛; 蒋元烨; 曹勤

doi:10.3969/j.issn.1001-5256.2020.08.044

非酒精性脂肪性肝病代谢组学与中医证候

DOI: 10.3969/j.issn.1001-5256.2020.08.044

上海中医药大学附属普陀医院消化内科

基金项目:

国家自然科学基金青年项目(81703879)；上海市卫计委临床研究专项面上项目(201840377,201940449)；普陀区科委自主创新项目(ptkwws201813,ptkwws201806)；上海中医药大学附属普陀医院重点专科(2016103A)；

详细信息

中图分类号: R259
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出版历程
- 出版日期: 2020-08-20

Metabonomics and traditional Chinese medicine syndrome of nonalcoholic fatty liver disease

Department of Gastroenterology, Putuo Hospital, Shanghai University of Traditional Chinese Medicine

Research funding:

摘要

摘要:
非酒精性脂肪性肝病(NAFLD)发病率逐年增加,是全球范围最常见的肝病之一。代谢组学继承了基因组学、蛋白质组学的研究思想,对生物体内所有代谢物进行定量分析,探索代谢物与生理病理变化的相对关系,为研究中医药诊治NAFLD开辟了新途径。总结了代谢组学与中医证侯在NAFLD中的研究进展,为进一步探索NAFLD提供新的思路与方法。
- 非酒精性脂肪性肝病 /
- 代谢组学 /
- 证候
Abstract:
The incidence rate of nonalcoholic fatty liver disease(NAFLD) is increasing year by year and NAFLD has become one of the most common liver diseases in the world.Metabolomics follows the research thoughts of genomics and proteomics and conducts a quantitative analysis of all metabolites in organisms to explore the association between metabolites and physiological and pathological changes,which provides a new way for studying the traditional Chinese medicine diagnosis and treatment of NAFLD.This article summarizes the research advances in metabolomics and traditional Chinese medicine syndromes in NAFLD,so as to provide new thoughts and methods for further exploration of NAFLD.
- non-alcoholic fatty liver disease /
- metabolomics /
- symptom complex

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参考文献(37)

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