钆塞酸二钠在肝胆手术术前评估中的应用

蒋家云; 李雪松; 马宽生

doi:10.3969/j.issn.1001-5256.2015.06.042

钆塞酸二钠在肝胆手术术前评估中的应用

DOI: 10.3969/j.issn.1001-5256.2015.06.042

第三军医大学西南医院全军肝胆外科研究所

基金项目:

国家自然科学基金(81272688,30972894)；重庆市应用开发计划重点项目(cstc2014yykf B10002)；重庆西南医院院管课题(普美显增强MRI定量评估所段储备功能的临床研究,SWH2014LC25)；

详细信息

中图分类号: R735.7
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出版历程
- 收稿日期: 2014-10-29
- 出版日期: 2015-06-20

Application of hepatobiliary-specific MRI contrast agent Gd-EOB-DTPA in preoperative evaluation of hepatobiliary patients

Institute of Hepatobiliary Surgery,Southwest Hospital,Third Military Medical University

Research funding:

摘要

摘要: 钆塞酸二钠（Gd-EOB-DTPA）是一种新型肝细胞特异性对比剂,经胆道和肾脏双通道排泄,具有非特异性细胞外对比剂和肝细胞特异性对比剂的双重特点,将动态期成像和肝胆特异期成像的特点结合可清晰地显示肝脏局灶性病变,可以在相对短的时间内对肝脏血流灌注、胆管成像、定性和检测肝脏局灶性病变、评估肝功能。国内外大量研究已证实肝胆特异性磁共振检查在肝癌尤其是小肝癌的定性诊断中明显优于磁共振成像、增强CT及超声检查。介绍了该对比剂的特点、在肝胆手术术前评估中的应用现状及展望。
- 肝肿瘤 /
- 磁共振成像 /
- 造影剂 /
- 钆塞酸二钠 /
- 综述
Abstract: Gd- EOB- DTPA,a newly applicable hepatocyte- specific contrast agent,is excreted through the biliary tract and the kidney,showing the characteristics of nonspecific extracellular contrast agent and hepatocyte- specific contrast agent. It can provide both dynamic and hepatobiliary images and has been rapidly accepted by clinicians for the diagnosis of liver lesions and preoperative evaluation. Gd- EOB-DTPA can fulfill hepatic perfusion imaging,cholangiography,detection and characterization of focal liver lesions,and evaluation of liver function within the same examination in a relatively short time window. A large number of domestic and foreign studies have confirmed that hepatobiliary- specific contrast- enhanced MRI is significantly superior to MRI scan,contrast- enhanced CT,and ultrasound in diagnosing hepatocellular carcinoma,especially small hepatocellular carcinoma. The features of Gd- EOB- DTPA and its current status and prospect of application in the preoperative evaluation of hepatocellular carcinoma are reviewed in this article.
- liver neoplasms /
- magetic resonance imaging /
- contrast media /
- Gd-EOB-DTPA /
- review

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参考文献(22)

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