Development of a prognostic factors model for severe hepatitis

Lu: RiYing; Li ShiXiong; Wu JiZhou; Zhu YuJia; Fu ShaoPing

Issue 10

Oct. 2012

Turn off MathJax

Article Contents

Abstract

References

Article Navigation > Journal of Clinical Hepatology > 2012 > 28(10): 789-792

PDF( 1179 KB)

Development of a prognostic factors model for severe hepatitis

Published Date: 2012-10-20

Abstract

Abstract

Objective To generate a prognostic factors model for severe hepatitis.Methods The clinical data of 145 in-patients with severe hepatitis who had been treated in the Eighth Affiliated Hospital of Guangxi Medical University from June 2008 to June 2011 were retrospectively analyzed.Logistic regression analysis was used to develop a prognostic factors model.Results Among the 145 patients, 54 recovered and 91 died (case fatality rate: 62.8%) .Logistic regression analysis identified hepatic encephalopathy, ascites, creatinine, ammonia, and prothrombin activity as independent prognostic factors of severe hepatitis.Conclusion A prognostic factors model composed of hepatic encephalopathy, ascites, creatinine, ammonia, and prothrombin activity, can accurately predict the short-term prognosis of patients with severe hepatitis.
- hepatitis,
- viral,
- human,
- prognosis

FullText(HTML)

References(10)

References

[1]明全, 邱绍勤, 陈长寅.人工肝支持系统治疗重型肝炎临床研究[J].中华肝脏病杂志, 2004, 12 (5) :315.

[2]中华医学会传染病与寄生虫病学分会、肝病学分会.病毒性肝炎防治方案[J].中华传染病杂志, 2001, 19 (1) :56-62.

[3]丁惠国, 郜桂菊, 陈涛, 等.影响重型病毒性肝炎患者预后的危险因素研究[J].临床肝胆病杂志, 2002, 18 (5) :297-299.

[4]赖宁, 郭树华, 张大志, 等.重型肝炎患者预后因素分析与评估系统研究[J].中华肝脏病杂志, 2005, 8 (13) :586-589.

[5]张南, 王宇明, 邓国宏, 等.慢性重型肝炎患者的预后因素分析及预后模型的建立[J].中华肝脏病杂志, 2005, 13 (10) :730-733.

[6]吕超, 陆建, 辛海光, 等.影响慢性重型肝炎预后相关指标的多因素回归分析[J].临床肝胆病杂志, 2008, 24 (6) :428-431.

[7]骆抗先.乙型肝炎基础和临床[M].北京:人民卫生出版社, 2001:602-627.

[8]Forman LM, Lucey MR.Predicting the prognosis of chronicliver disease:an evolution from child to MELD.Mayo End-stage Liver Disease[J].Hepatology, 2001, 33 (2) :473-475.

[9]陆伦根.肝性脑病的发病机制[J].中华肝脏病杂志, 2004, 12 (5) :304.

[10]汪杨, 辛桂杰, 王峰, 等.重型肝炎血氨检测的价值的研究[J].临床肝胆病杂志, 2008, 24 (3) :185-186.

Relative Articles

[1]	Di WU, Dahua DAI, Wenmei LIANG, Bao FU, Xiaoyun FU. Clinical features of acute pancreatitis in pregnancy and related risk factors[J]. Journal of Clinical Hepatology, 2024, 40(5): 1009-1015. doi: 10.12449/JCH240522
[2]	Decai KONG, Xiaojing ZHANG, Yangguang YUN, Haoyu DUAN, Junfeng YE. Risk factors for biliary stricture and prognosis after orthotopic liver transplantation[J]. Journal of Clinical Hepatology, 2024, 40(11): 2253-2259. doi: 10.12449/JCH241119
[3]	Qiaoling WANG, Qingsheng LIANG, Ang HUANG, Xingran ZHAI, Huang XIE, Ying SUN, Zhengsheng ZOU. Influencing factors for the prognosis of biopsy proven patients with chronic drug-induced liver injury: An analysis of 255 cases[J]. Journal of Clinical Hepatology, 2022, 38(6): 1334-1340. doi: 10.3969/j.issn.1001-5256.2022.06.022
[4]	Bingbing ZHU, Jinxiang YANG, Qun ZHANG, Fangyuan GAO, Xianbo WANG. Risk factors for the 90-day prognosis of patients with type I hepatorenal syndrome and establishment of a predictive model[J]. Journal of Clinical Hepatology, 2022, 38(7): 1561-1565. doi: 10.3969/j.issn.1001-5256.2022.07.019
[5]	Wanshu LIU, Lijun SHEN, Qinghui ZHAI, Shaojie XIN, Shaoli YOU. Risk factors for acute variceal bleeding in acute-on-chronic liver failure and its influence on prognosis[J]. Journal of Clinical Hepatology, 2022, 38(11): 2532-2536. doi: 10.3969/j.issn.1001-5256.2022.11.018
[6]	Siqin LIU, Xiaomei WANG, Xia LI, Luwen LIANG, Ke WANG, Rui WANG. Covert hepatic encephalopathy in liver cirrhosis: Risk factors and prognosis[J]. Journal of Clinical Hepatology, 2022, 38(2): 359-364. doi: 10.3969/j.issn.1001-5256.2022.02.020
[7]	Zhang DaLi, Feng DanNi, Zhang LiJuan, Tang RuJia, He Xi, Zhou Xia, Gao YinJie, Liu ZhenWen, Liu HongLing. Risk factors for recurrence after liver transplantation in patients with hepatocellular carcinoma and their prognosis[J]. Journal of Clinical Hepatology, 2020, 36(9): 1985-1989. doi: 10.3969/j.issn.1001-5256.2020.09.015
[8]	Li Ying, Zhan Jing, Wang ZhongFeng. Prognostic factors for patients with hepatitis B virus-related acute-on-chronic liver failure[J]. Journal of Clinical Hepatology, 2017, 33(3): 497-501. doi: 10.3969/j.issn.1001-5256.2017.03.020
[9]	Wang FengJiao, Liu MingJiang, Wu RuiHong, Niu JunQi. A multivariate logistic regression analysis of short-term prognosis of patients with hepatic encephalopathy[J]. Journal of Clinical Hepatology, 2017, 33(4): 711-714. doi: 10.3969/j.issn.1001-5256.2017.04.022
[10]	Ma ShiJie, Zou ShaoJing, Luo XiaoLing, Li QianJun, Huang JiaSheng. Prognostic factors for transcatheter arterial chemoembolization in patients with hepatocellular carcinoma[J]. Journal of Clinical Hepatology, 2016, 32(1): 80-83. doi: 10.3969/j.issn.1001-5256.2016.01.013
[11]	Huang Yu, Huang Di, Liu Shuo, Weng JieFeng, Zhang Shuai, Zhang Qiang, Mai ZhenHao, Gu WeiLi. Clinical features of non- B non- C hepatocellular carcinoma and virus-associated hepatocellular carcinoma and re-lated prognostic factors[J]. Journal of Clinical Hepatology, 2016, 32(3): 514-517. doi: 10.3969/j.issn.1001-5256.2016.03.024
[12]	Shi XinXing, Zhang YanQiong, Zhu Peng, Yan GuoHua, Zhang ZhangJiang, Wang YuMing. Prognostic risk factors in patients with hepatitis B virus- related acute- on- chronic liver failure[J]. Journal of Clinical Hepatology, 2016, 32(4): 700-705. doi: 10.3969/j.issn.1001-5256.2016.04.018
[13]	Cui YanPing, Li QingFang, Li QingYan, Liu ChunHua, Wang WeiHong, Yuan JianGuo, Wang SiKui. Logistic regression analysis of prognostic risk factors for hepatic encephalopathy[J]. Journal of Clinical Hepatology, 2016, 32(1): 135-138. doi: 10.3969/j.issn.1001-5256.2016.01.026
[14]	Gao Rui, Liu ZhongJing, Chen Fei, Gao Lei, Jiang ChuanWu. Multivariate regression analysis of risk factors for HBV-related primary liver cancer[J]. Journal of Clinical Hepatology, 2014, 30(4): 370-372. doi: 10.3969/j.issn.1001-5256.2014.04.021
[15]	Pang XueQin, Chen WeiChang, Feng Huang, Tian WenYan. Risk factors for non- alcoholic fatty liver disease: a multivariate analysis[J]. Journal of Clinical Hepatology, 2014, 30(9): 903-905. doi: 10.3969/j.issn.1001-5256.2014.09.016
[16]	Wu XiaoQing, Wan Hong. Causes of liver failure and impact analysis of prognostic risk factors[J]. Journal of Clinical Hepatology, 2013, 29(4): 294-296+304.
[17]	Zhang DongQing, Chen Li, Gan QiaoRong, Zhou Rui, Huang JianRong, Pan Chen. Prognostic factors for hepatitis B acute-on-chronic liver failure[J]. Journal of Clinical Hepatology, 2012, 28(10): 740-743.
[18]	Liu HongHong, Fu JunLiang, Fu BaoYun, Zhang Zheng, Xu RuoNan, Luo ShengQiang, Shi Ming, Li YongGang, Wang FuSheng. The pathogenesis and risk factors related to prognosis of primary biliary cirrhosis[J]. Journal of Clinical Hepatology, 2012, 28(2): 153-155.
[19]	Lu: Chao, Lu Jian, Xin HaiGuang, Wang JunXue. Logistic regression analysis of multiple factor that may influence the prognosis of chronic hepatic failure[J]. Journal of Clinical Hepatology, 2008, 24(6): 428-431.
[20]	Ding HuiGuo, Gao GuiJu, Chen Tao, Jin Rui. Prognosis of Severe Types of Virous Hepatitis: Study on Mutiple Risk Factors.[J]. Journal of Clinical Hepatology, 2002, 18(5): 297-299.

Supplements(0)

Cited By

Proportional views

Proportional views

通讯作者: 陈斌, bchen63@163.com

1.
沈阳化工大学材料科学与工程学院沈阳 110142

Get Citation

PDF

XML

Article Metrics

Article views (3350) PDF downloads(694)

Development of a prognostic factors model for severe hepatitis

Abstract

References

Relative Articles

Proportional views

Catalog

通讯作者: 陈斌, bchen63@163.com

Article Metrics

Proportional views

Related

Development of a prognostic factors model for severe hepatitis

Abstract

References

Relative Articles

Proportional views

Catalog

通讯作者: 陈斌, bchen63@163.com

Article Metrics

Proportional views

Related

About Journal

Submission Guideline

Journal Online

Hepatobiliary College

Guidelines

Export File

Citation

Format

Content