中文English
ISSN 1001-5256 (Print)
ISSN 2097-3497 (Online)
CN 22-1108/R
Issue 5
May  2002

影响重型病毒性肝炎患者预后的危险因素研究

  • Published Date: 2002-05-20
  • To analyse mutiple risk factors of predictive survive of severe types virous hepatitis, and to make a scored system which could be determined patient's prognosis. One hundred seventy patients at the end of hospitalization were divided into alive group (n=45) and dead group (n=125) . 133 patients were men, and 37 patients were women. The average age was 43 5 years old (range from 8 to 78) . Twenty clinical and laboratory parameters were investigated as predictive risk factors. Univariate analysis was first made. Variables reaching statistical significance ( P <0 05) were subsequently introduced in logistic regression to identify the independent risk factors for patient's survive. The methods of statistical analysis were performed with SPSS 6 0 for WINDOWS statistical package. Nine clinical and laboratory parameters, PTA, serum , hepatic encephalopathy, clinical types of serious virous hepatitis, GI bleeding, hepatic kinedy sydrome, total bilirubin serum BUN, and ascites were closely related to prognosis of severe type of virous hepatitis by analysis of univariate. Four independent risk factors, PTA, serum , hepatic encephalopathy, and clinical types of serious virous hepatitis were obtained by Logistic regression. A scored system was made accroding to those 4 parameters. The threshold score of death was 5. The coincidence rate was 80% by retrospective study of 170 patients with serious virous hepatitis. PTA, serium , hepatic encephalopathy, and clinical types of serious virous hepatitis are independent predictive factors in patients with serious virous hepatitis. It is important that the risk factors should be early assessed, ward off, and treated. The treatment strategy can be determined and the medical resources can be reasonably used according to this score system.

     

  • [1]侯岳声重型肝炎预后因素分析[J].汕头大学医学院学报, 1999, 12 (3) ∶19-21.
    [2]周凤, 王军, 刘自贵, 等重症肝炎88例预后分析[J].华西医学, 1997, 12 (4) ∶407-408.
    [3]姚履枫, 张月英重症肝炎402例预后分析[J].福建医药杂志, 1997, 19 (5) ∶16-17.
    [4]QiuJG , DelanyHM , TheEL , etal.Contrastingeffectsofidenticalnu trientsgivenparenterallyorenterallyafter70%hepatectomybacterialtransloction[J].Nutrition, 1997, 13∶473-474.
    [5] RiordanS .M ., WilliamsR .Acuteliverfailure:targetdartificialandhepatocyte-basedsupportofliverregenerationandreversalofmultiorganfailure.JHepatol, 2000, 32 (suppl.1) 63-76.
    [6] 周晓琳, 丁惠国肝硬化患者低钠血症临床分析[J].中国临床医生, 2001, 6∶167-168.
    [7]赵国根, 谢润生, 朱秀亚, 等重型肝炎和肝硬化合并细菌感染临床分析[J].中华医院感染学杂志, 2000, 10 (1) ∶25-26.
    [8]KnausWA , DraperEA , WangnerDP , etal.Prognosisinacuteorgan-systemfailure[J].AnnSurg, 1985, 202∶685-687.
  • 加载中

Catalog

    通讯作者: 陈斌, bchen63@163.com
    • 1. 

      沈阳化工大学材料科学与工程学院 沈阳 110142

    1. 本站搜索
    2. 百度学术搜索
    3. 万方数据库搜索
    4. CNKI搜索

    Article Metrics

    Article views (2170) PDF downloads(912) Cited by()
    Proportional views
    Related

    /

    DownLoad:  Full-Size Img  PowerPoint
    Return
    Return