Objective To observe the influence of treatment in patients' urine volume, liver and renal function by warming the Kidney and promoting diuresis with Alprostadil in patients with liver cirrhosis complicated with hepato-renal syndrome.Methods 57 patients with liver cirrhosis complicated with hepato-renal syndrome were randomly divided into the treatment group and control group.The control group of 28 cases was treated with the conventional therapyby limiting the sodium intake, supporting, protecting the liver, diuresis, adding albumin, antibiotics, applying vasodilator agents and hepatocyte growth-promoting factors and symptomatic treatmentby intravenous infusion of Alprostadil 10 μg.The treatment group was treated with the conventional therapy with oral decoction by warming the kidney and promoting diuresis.The course of treatment was 3 weeks in both the groups.After 1 treatment course, observe the change of the clinical symptoms, ascites, the liver and renal function and urine volume.Results Clinical curative effect was compared.The effective rate was 86.21% in the treatment group and 67.86% the control group.The difference was statistically significant (P< 0.05) .Conclusion The treatment by warming the kidney and promoting diuresis with Alprostadil in liver cirrhosis complicated with hepato-renal syndrome can improve the clinical symptoms, reduce the ascites subsiding time, improve the liver and renal function, delay and stop the progress of the disease.
DownLoad: