中文English
ISSN 1001-5256 (Print)
ISSN 2097-3497 (Online)
CN 22-1108/R
Issue 4
Apr.  2002

原因不明性肝炎血清中TTVDNA的检出及其临床意义

Research funding:

 

  • Published Date: 2002-04-20
  • To investigate TTV infection among patients with hepatitis of unknown etiology and its clinical significance. A nested polymerase chain reaction (PCR) assay with primers from ORF1 of TTV genome was established to detect TTV DNA in 50 patients with hepatitis of unknown etiology, 40 health persons and 30 HBV carriers. The positive rate of TTV DNA in patients with hepatitis of unknown etiology, health persons and in HBV carriers were 32% (16/50) , 5% (2/40) and 6 7% (2/30) , respectively. It had statistical difference between them ( P <0 05) . Among 16 patients with TTV DNA positive response, 12 cases were chronic hepatitis (12/16, 75%) . TTV infection would be one of the major causes of hepatitis with unknown etiology in this areas.

     

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