Changes of hepatic ultrastructure in patients with diabetes mellitus

Qin YingFen; Xian Su; Wei MinYi; Luo ZuoJie; Chen QingYun; Wang NaiZun

Issue 4

Apr. 2000

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Article Navigation > Journal of Clinical Hepatology > 2000 > 16(4): 241-243

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糖尿病人肝脏的超微结构研究

Published Date: 2000-04-20

Abstract

Abstract

Objective:To study the changes of hepatic ultrastructure in patients with diabetes mellitus.Methods:Liver biopsy and pathological examination were carried out in 20 diabetes mellitus patients.Result Under light microscope, It showed that nuclear glycogen cavity, fatty degeneration and interstitial fibrosis.Whereas electron microscope:nuclear glycogen granules;glycogen granules in cytoplasm increase;rough endoplasmic reticulum degranulation;smooth endoplasmic reticulum expansion;mitochondrial swelling, crista disorder or electron density increase;fatty degeneration;interstitial fibrosis.Conclusion:The most characteristic change of hepatic ultrastructure is nuclear glycogen granules in diabetes mellitus.
- Diabetes mellitus,
- Liver,
- Ultrastructure

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[]〔4〕贾雪梅 , 齐易祥 , 王惠珠 , 等 .实验性糖尿病对小鼠肝脏酶组织化学和超微结构的影响〔J〕 .解剖学杂志 , 1995 , 18 (5 ) ∶45 1.

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糖尿病人肝脏的超微结构研究

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