Traditional Chinese medicine (TCM) has certain advantages in the treatment of chronic liver diseases, especially chronic inflammatory injury and liver fibrosis.However, the studies on medicinal components and action mechanism of TCM prescriptions are confronted with a great challenge.The computation...

The compound of active ingredients of traditional Chinese medicine (TCM) , whose material base is relatively clear, adheres to the concept and advantages of formula compatibility of TCM.Thus, it is an important approach to modern TCM research.The significance of research on compound of TCM component...

Since the prevalence of nonalcoholic fatty liver disease (NAFLD) has been rising in recent years, more and more attention is being paid to clinical trials of traditional Chinese medicine (TCM) treatment, which is one of the main methods for treating NAFLD.According to the reported clinical trials, c...

Portal hypertension, endotoxemia, hepatic encephalopathy, and ascites are common complications of liver cirrhosis, and there are few effective treatment methods for them in modern medicine.Common concepts, methods, and application of external therapy of traditional Chinese medicine (TCM) , such as a...

Budd- Chiari syndrome (BCS) is a rare liver disease, and there are mutual influences between BCS and pregnancy.The relationship between BCS and pregnancy is systematically discussed, and the points we should pay attention to in the diagnosis and treatment of this disease are pointed out as follows:F...

Objective To investigate the treatment methods for chronic hepatitis B (CHB) with diabetes.Methods Sixty- eight patients with CHB accompanied by diabetes who were hospitalized in the division of infectious diseases of our hospital from January 2008 to December 2012 were included in the study.These p...

Objective To observe the clinical efficacy of entecavir combined with Xinganbao capsules in the treatment of liver cirrhosis among patients with chronic hepatitis B (CHB) .Methods Sixty CHB patients with liver cirrhosis were randomly divided into two groups:treatment group (n = 30) given entecavir c...

Objective To observe the therapeutic efficacy of Ganshuang granules in the treatment of hepatic fibrosis.Methods Sixty- eight patients with cirrhosis due to chronic hepatitis B (CHB) were divided into experimental group (n = 34) and control group (n = 34) .Both groups received adefovir dipivoxil for...

Objective To investigate the relationship between percentages of T lymphocytes in peripheral blood and deficiency of vital qi in patients with hepatitis B virus- related acute- on- chronic liver failure (HBV- ACLF) .Methods Forty patients with early- stage HBV-ACLF were enrolled as liver failure gro...

Objective To observe the pharmacodynamic characteristics of Danggui Buxue decoction (containing Angelica sinensis) and its separated recipes in treating liver fibrosis and angiogenesis.Methods Forty- eight Wistar rats were randomly divided into 6 groups:normal group, model group, Danggui Buxue decoc...

Objective To evaluate the clinical effect of integrated traditional Chinese and Western medicine therapy based on Qingyi Huaji (QYHJ) formula (for clearing the pancreas and dissolving the stasis) in the elderly patients with pancreatic cancer by a retrospective study and to explore a feasible treatm...

Objective To investigate the inhibitory effect of Anfate on the expression of transforming growth factor β1 (TGFβ1) /small mothers against decapentaplegic homolog 2 (Smad2) signaling pathway in the treatment of hepatic fibrosis in mice.Methods Ninety healthy male ICR mice were randomly divided into ...

Objective To observe the effects of Ruangan Huajian granules on the serum levels of matrix metalloproteinase-13 (MMP-13) and tissue inhibitor of metalloproteinase- 1 (TIMP- 1) and the mRNA expression of MMP- 13 and TIMP- 1 in liver tissue among C57 mice with hepatic fibrosis.Methods Forty C57 mice w...

Objective To investigate the role of Jak /Stat pathway in the CCl4- induced rat liver fibrosis model and the molecular action mechanism of Fuzheng Huayu recipe in the treatment of liver fibrosis.Methods Experimental rats were randomly divided into control group, CCl4- induced liver fibrosis model gr...

Objective Data on liver stiffness measurement (LSM) in chronic hepatitis B (CHB) patients with persistently normal alanine aminotransferase (ALT) (PNALT) and persistently or intermittently elevated ALT (PIEALT) were limited.In this study, we aimed to assess LSMs in these patients and determine the p...

Objective To investigate the relationship of serum adiponectin level with body fat, blood lipids, and insulin resistance (IR) in the patients with chronic hepatitis B (CHB) and patients with CHB and fatty liver.Methods Twenty patients CHB, 20 cases of CHB with fatty liver, and 18 healthy controls we...

Objective To analyze the early warning indicators of tuberculous peritonitis (TBP) in patients with cirrhotic ascites.Methods A retrospective analysis was performed on the clinical data of 62 patients with cirrhotic ascites hospitalized in the Second Affiliated Hospital of Chongqing Medical Universi...

Objective To evaluate the efficacy and safety of Baquting (hemocoagulase for injection) for hemostasis in biliary surgery.Methods A total of 240 patients were divided into hemocoagulase group (n = 120) and control group (n = 120) .Normal saline was used instead of hemocoagulase in the control group....

Objective To investigate the preventive and therapeutic effects of lamivudine and entecavir on hepatitis B virus (HBV) reactivation among non- Hodgkin lymphoma (NHL) patients with chronic HBV infection during chemotherapy.Methods From January 2008 to April 2013, a total of 94 NHL patients with HBV i...

Objective To investigate the short- term prognosis in hepatitis B virus (HBV) - related acute- on- chronic liver failure (ACLF) treated with artificial liver support system (ALSS) and its relationship with clinical indices including HBeAg and to provide reference for the timely, accurate prognostic ...

Hepatitis B surface antibody (HBsAb) is formed in response to hepatitic B virus (HBV) infection, which is a typical characteristic of virus clearance.It is theoretically impossible to detect sequential expression of hepatitis B surface antigen (HBsAg) and HBsAb in the same patient.In recent years, h...

There has been rapid research progress in the biological characteristics and function of osteopontin (OPN) over the last 20 years.OPN, synthesized and secreted by many tissue cells, has a similar structure as many matrix proteins and possesses the functional characteristics of cytokines.It is involv...

With the development of radiotherapy techniques, the efficacy of radiotherapy for liver tumors has been improved, and radiotherapy can be considered as an alternative treatment for patients who are not suitable for surgery.The progress in liver tumor radiotherapy reported in the 55th annual meeting ...