以亚急性肝衰竭为首发表现的IgG4相关性自身免疫性肝炎1例报告

蒋黎; 刘慧敏; 毛青

doi:10.3969/j.issn.1001-5256.2022.01.028

以亚急性肝衰竭为首发表现的IgG4相关性自身免疫性肝炎1例报告

DOI: 10.3969/j.issn.1001-5256.2022.01.028

陆军军医大学西南医院全军感染病研究所，重庆市感染病研究重点实验室，重庆 400038

基金项目:

国家科技重大专项 (2017ZX10203201-006);

国家科技重大专项 (2017ZX10202201-00-010)

利益冲突声明：所有作者均声明不存在利益冲突。

作者贡献声明：刘慧敏负责文章设计，病例资料分析，撰写论文; 蒋黎参与收集数据，修改论文; 毛青负责拟定写作思路，指导撰写文章并最后定稿。

详细信息

通信作者:
刘慧敏，liuhuimin_412@sina.cn

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- 被引次数: 0
出版历程
- 收稿日期: 2021-05-12
- 录用日期: 2021-05-31
- 出版日期: 2022-01-20

IgG4-related autoimmune hepatitis with subacute liver failure as the initial manifestation: A case report

Chongqing Key Laboratory of Infectious Disease Research, Institute of Infectious Diseases of PLA, Southwest Hospital, Army Medical University, Chongqing 400038, China

Research funding:

the Major Program of National Science and Technology (2017ZX10203201-006);

the Major Program of National Science and Technology (2017ZX10202201-00-010)

摘要

- 肝炎, 自身免疫性 /
- 肝功能衰竭, 急性 /
- 免疫球蛋白G
- Hepatitis, Autoimmune /
- Liver Failure, Acute /
- Immunoglobulin G

HTML全文

图 1 肝组织活检病理

注：a，汇管区炎症，界面炎(HE染色，×400);b，多小叶坏死(HE染色，×100);c，IgG染色(×400);d，IgG4染色(×400); e，网染(×200);f，电镜(×4000);g，电镜(×2000);h，电镜(×2000)。

下载: 全尺寸图片幻灯片

图 2 IgG与IgG4随访情况

下载: 全尺寸图片幻灯片

表 1 血生化指标随访情况

时间	ALT(U/L)	AST(U/L)	GGT(U/L)	ALP(U/L)	Alb(g/L)	TBil(μmol/L)	DBil(μmol/L)	PT-INR	PLT(×10⁹/L)
2021/2/8	717	1220	348	553	22.10	305.18	222.97	1.19	94
2021/2/13	228	251	247	370	25.26	301.68	212.30	1.63	97
2021/2/24	165	259	261	390	33.8	436.35	326.05	1.70	98
2021/3/4	107	109	237	229	29.43	233.89	179.00	1.41	41
2021/3/11	72	89	233	192	31.01	152.01	114.50	1.32	65
2021/3/15	71	84	254	215	30.50	124.40	82.75	1.49	70
2021/4/3	75	386	385	350	22.00	158.30	115.80	1.34	73
2021/4/8	101	391	302	335	29.50	169.00	108.60	1.50	65
2021/4/16	102	120	235	240	31.20	138.40	88.90	1.48	79
2021/4/22	79	79	192	198	25.30	134.70	98.50	1.22	73
2021/4/27	59	58	160	146	29.70	87.70	65.80	1.46	65

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参考文献(21)

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