留言板

尊敬的读者、作者、审稿人, 关于本刊的投稿、审稿、编辑和出版的任何问题, 您可以本页添加留言。我们将尽快给您答复。谢谢您的支持!

姓名
邮箱
手机号码
标题
留言内容
验证码

2019年—2020年胰腺癌放射治疗新进展

任刚 王颖杰

任刚, 王颖杰. 2019年—2020年胰腺癌放射治疗新进展[J]. 临床肝胆病杂志, 2021, 37(3): 733-736. DOI: 10.3969/j.issn.1001-5256.2021.03.048
引用本文: 任刚, 王颖杰. 2019年—2020年胰腺癌放射治疗新进展[J]. 临床肝胆病杂志, 2021, 37(3): 733-736. DOI: 10.3969/j.issn.1001-5256.2021.03.048
REN G, WANG YJ. Advances in radiotherapy for pancreatic cancer from 2019 to 2020 [J]. J Clin Hepatol, 2021, 37(3): 733-736. DOI: 10.3969/j.issn.1001-5256.2021.03.048
Citation: REN G, WANG YJ. Advances in radiotherapy for pancreatic cancer from 2019 to 2020 [J]. J Clin Hepatol, 2021, 37(3): 733-736. DOI: 10.3969/j.issn.1001-5256.2021.03.048

2019年—2020年胰腺癌放射治疗新进展

DOI: 10.3969/j.issn.1001-5256.2021.03.048
详细信息
    作者简介:

    任刚(1980—),男,副主任医师,博士,主要从事胰腺恶性肿瘤放射治疗研究

    通讯作者:

    王颖杰,wangyj9999@163.com

  • 利益冲突声明:所有作者均声明不存在利益冲突。
  • 作者贡献声明:任刚负责文献检索,撰写论文;王颖杰负责拟定写作思路,指导撰写文章并最后定稿。
  • 中图分类号: R735.9

Advances in radiotherapy for pancreatic cancer from 2019 to 2020

  • 摘要: 随着放疗设备、影像技术、人工智能等方面的迅速发展,放疗已进入精准时代。放疗是胰腺癌治疗的重要手段之一,近期在相关放疗理念、技术模式方面进展很快。结合目前放疗领域专家所关注的胰腺癌放疗技术新进展、放疗剂量模式改变等热点问题,回顾近期相关文献加以总结分析,归纳提示多模态影像对指导胰腺癌放疗有重要作用,放疗剂量模式向高剂量少分次方向发展,新辅助放疗的作用得到进一步证实,多药联合的强力化疗方案是胰腺癌放疗的主要联合方式。
  • [1] XU XH, ZENG XY, WANG LJ, et al. The disease burden of pancreatic cancer in China in 1990 and 2017[J]. Chin J Epidemiol, 2019, 40(9): 1084-1088.

    徐晓慧, 曾新颖, 王黎君, 等. 1990年与2017年中国胰腺癌疾病负担分析[J]. 中华流行病学杂志, 2019, 40(9): 1084-1088.
    [2] PILGRIM C, TE MARVELDE L, STUART E, et al. Population-based analysis of treatment patterns and outcomes for pancreas cancer in Victoria[J]. ANZ J Surg, 2020, 90(9): 1677-1682. DOI: 10.1111/ans.15721
    [3] CARAVATTA L, CELLINI F, SIMONI N, et al. Magnetic resonance imaging (MRI) compared with computed tomography (CT) for interobserver agreement of gross tumor volume delineation in pancreatic cancer: A multi-institutional contouring study on behalf of the AIRO group for gastrointestinal cancers[J]. Acta Oncol, 2019, 58(4): 439-447. DOI: 10.1080/0284186X.2018.1546899
    [4] DIFFENDERFER ES, VERGINADIS Ⅱ, KIM MM, et al. Design, implementation, and in vivo validation of a novel proton FLASH radiation therapy system[J]. Int J Radiat Oncol Biol Phys, 2020, 106(2): 440-448. DOI: 10.1016/j.ijrobp.2019.10.049
    [5] BOURHIS J, SOZZI WJ, JORGE PG, et al. Treatment of a first patient with FLASH-radiotherapy[J]. Radiother Oncol, 2019, 139: 18-22. DOI: 10.1016/j.radonc.2019.06.019
    [6] XIANG M, HEESTAND GM, CHANG DT, et al. Neoadjuvant treatment strategies for resectable pancreas cancer: A propensity-matched analysis of the National Cancer Database[J]. Radiother Oncol, 2020, 143: 101-107. DOI: 10.1016/j.radonc.2020.01.007
    [7] TCHELEBI LT, LEHRER EJ, TRIFILETTI DM, et al. Conventionally fractionated radiation therapy versus stereotactic body radiation therapy for locally advanced pancreatic cancer(CRiSP): An international systematic review and meta-analysis[J]. Cancer, 2020, 126(10): 2120-2131. DOI: 10.1002/cncr.32756
    [8] BERTHOLET J, HUNT A, DUNLOP A, et al. Comparison of the dose escalation potential for two hypofractionated radiotherapy regimens for locally advanced pancreatic cancer[J]. Clin Transl Radiat Oncol, 2019, 16: 21-27. DOI: 10.1016/j.ctro.2019.03.001
    [9] AZIZ H, ZEESHAN M, JIE T, et al. Neoadjuvant chemoradiation therapy is associated with adverse outcomes in patients undergoing pancreaticoduodenectomy for pancreatic cancer[J]. Am Surg, 2019, 85(11): 1276-1280. DOI: 10.1177/000313481908501136
    [10] KAMARAJAH SK, BUNDRED JR, BOYLE C, et al. Impact of neoadjuvant therapy on post-operative pancreatic fistula: A systematic review and meta-analysis[J]. ANZ J Surg, 2020, 90(11): 2201-2210. DOI: 10.1111/ans.15885
    [11] THANIKACHALAM K, DAMARLA V, SEIXAS T, et al. Neoadjuvant Phase Ⅱ trial of chemoradiotherapy in patients with resectable and borderline resectable pancreatic cancer[J]. Am J Clin Oncol, 2020, 43(6): 435-441. DOI: 10.1097/COC.0000000000000688
    [12] TRAN NH, SAHAI V, GRIFFITH KA, et al. Phase 2 trial of neoadjuvant FOLFIRINOX and intensity modulated radiation therapy concurrent with fixed-dose rate-gemcitabine in patients with borderline resectable pancreatic cancer[J]. Int J Radiat Oncol Biol Phys, 2020, 106(1): 124-133. DOI: 10.1016/j.ijrobp.2019.08.057
    [13] EGUCHI H, TAKEDA Y, TAKAHASHI H, et al. A prospective, open-label, multicenter phase 2 trial of neoadjuvant therapy using full-dose gemcitabine and S-1 concurrent with radiation for resectable pancreatic ductal adenocarcinoma[J]. Ann Surg Oncol, 2019, 26(13): 4498-4505. DOI: 10.1245/s10434-019-07735-8
    [14] VERSTEIJNE E, SUKER M, GROOTHUIS K, et al. Preoperative chemoradiotherapy versus immediate surgery for resectable and borderline resectable pancreatic cancer: Results of the dutch randomized phase Ⅲ PREOPANC trial[J]. J Clin Oncol, 2020, 38(16): 1763-1773. DOI: 10.1200/JCO.19.02274
    [15] LUTSYK M, BEN-YOSEF R. The role of radiotherapy in resected r0/r+ pancreatic cancer: A real-life single-institution experience[J]. Am J Clin Oncol, 2020, 43(3): 187-192. DOI: 10.1097/COC.0000000000000653
    [16] KAMARAJAH SK, SONNENDAY CJ, CHO CS, et al. Association of adjuvant radiotherapy with survival after margin-negative resection of pancreatic ductal adenocarcinoma: A propensity-matched National Cancer Database (NCDB) Analysis[J]. Ann Surg, 2021, 273(3): 587-594. DOI: 10.1097/SLA.0000000000003242
    [17] SHEN ZT, ZHOU H, LI AM, et al. Clinical outcomes and prognostic factors of stereotactic body radiation therapy combined with gemcitabine plus capecitabine for locally advanced unresectable pancreatic cancer[J]. J Cancer Res Clin Oncol, 2020, 146(2): 417-428. DOI: 10.1007/s00432-019-03066-z
    [18] ARCELLI A, GUIDO A, BUWENGE M, et al. Higher biologically effective dose predicts survival in sbrt of pancreatic cancer: A multicentric analysis (PAULA-1)[J]. Anticancer Res, 2020, 40(1): 465-472. DOI: 10.21873/anticanres.13975
    [19] ZHANG AM, CHANG XY, LI WG, et al. Clinical effect of CyberKnife radiosurgery in locally advanced pancreatic cancer or pancreatic cancer with distant metastasis[J]. J Clin Hepatol, 2019, 35(1): 143-146. DOI: 10.3969/j.issn.1001-5256.2019.01.027

    张爱民, 常小云, 李文刚, 等. 射波刀治疗局部进展期及合并远处转移胰腺癌的效果分析[J]. 临床肝胆病杂志, 2019, 35(1): 143-146. DOI: 10.3969/j.issn.1001-5256.2019.01.027
    [20] SCORSETTI M, COMITO T, FRANCESCHINI D, et al. Is there an oligometastatic state in pancreatic cancer? Practical clinical considerations raise the question[J]. Br J Radiol, 2020, 93(1106): 20190627. DOI: 10.1259/bjr.20190627
    [21] SHI W, JIANG R, LIANG F, et al. Definitive chemoradiotherapy and salvage chemotherapy for patients with isolated locoregional recurrence after radical resection of primary pancreatic cancer[J]. Cancer Manag Res, 2019, 11: 5065-5073. DOI: 10.2147/CMAR.S202543
    [22] LI Y, LIU W, ZHAO L, et al. The main bottleneck for non-metastatic pancreatic adenocarcinoma in past decades: A population-based analysis[J]. Med Sci Monit, 2020, 26: e921515.
    [23] KHATTAB A, PATRUNI S, ABEL S, et al. Long-term outcomes by response to neoadjuvant chemotherapy or chemoradiation in patients with resected pancreatic adenocarcinoma[J]. J Gastrointest Oncol, 2019, 10(5): 918-927. DOI: 10.21037/jgo.2019.07.02
    [24] GARNIER J, EWALD J, MARCHESE U, et al. Outcomes of patients with initially locally advanced pancreatic adenocarcinoma who did not benefit from resection: A prospective cohort study[J]. BMC Cancer, 2020, 20(1): 203. DOI: 10.1186/s12885-020-6690-1
    [25] PARR E, DU Q, ZHANG C, et al. Radiomics-based outcome prediction for pancreatic cancer following stereotactic body radiotherapy[J]. Cancers (Basel), 2020, 12(4)L 1051. DOI: 10.3390/cancers12041051
    [26] SIMPSON G, SPIELER B, DOGAN N, et al. Predictive value of 0.35 T magnetic resonance imaging radiomic features in stereotactic ablative body radiotherapy of pancreatic cancer: A pilot study[J]. Med Phys, 2020, 47(8): 3682-3690. DOI: 10.1002/mp.14200
    [27] SU W, REN S, ZHU X, et al. Standardized thresholds of volume-based PET/CT parameters predicting survival of patients with pancreatic head cancer treated with stereotactic body radiation therapy[J]. Ann Nucl Med, 2020, 34(6): 379-387. DOI: 10.1007/s12149-020-01454-x
    [28] INCERTI E, VANOLI EG, BROGGI S, et al. Early variation of 18-fluorine-labelled fluorodeoxyglucose PET-derived parameters after chemoradiotherapy as predictors of survival in locally advanced pancreatic carcinoma patients[J]. Nucl Med Commun, 2019, 40(10): 1072-1080. DOI: 10.1097/MNM.0000000000001065
  • 加载中
计量
  • 文章访问数:  27
  • HTML全文浏览量:  280
  • PDF下载量:  40
  • 被引次数: 0
出版历程
  • 收稿日期:  2020-08-25
  • 修回日期:  2020-09-27
  • 刊出日期:  2021-03-16
  • 分享
  • 用微信扫码二维码

    分享至好友和朋友圈

目录

    /

    返回文章
    返回