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新型冠状病毒肺炎合并肝损伤的发生机制

李璐 李爽 陈煜

李璐, 李爽, 陈煜. 新型冠状病毒肺炎合并肝损伤的发生机制[J]. 临床肝胆病杂志, 2021, 37(1): 209-211. DOI: 10.3969/j.issn.1001-5256.2021.01.046
引用本文: 李璐, 李爽, 陈煜. 新型冠状病毒肺炎合并肝损伤的发生机制[J]. 临床肝胆病杂志, 2021, 37(1): 209-211. DOI: 10.3969/j.issn.1001-5256.2021.01.046
LI L, LI S, CHEN Y. Pathogenesis of coronavirus disease 2019 with liver injury[J]. J Clin Hepatol, 2021, 37(1): 209-211. DOI: 10.3969/j.issn.1001-5256.2021.01.046
Citation: LI L, LI S, CHEN Y. Pathogenesis of coronavirus disease 2019 with liver injury[J]. J Clin Hepatol, 2021, 37(1): 209-211. DOI: 10.3969/j.issn.1001-5256.2021.01.046

新型冠状病毒肺炎合并肝损伤的发生机制

DOI: 10.3969/j.issn.1001-5256.2021.01.046
基金项目: 

国家重点研发计划资助 2017YFA0103000

国家科技重大专项“艾滋病和病毒性肝炎等重大传染病防治” 2017ZX10203201-005

北京市医院管理局临床医学发展专项经费资助 ZYLX201806

白求恩医学科学研究基金资助项目 SG068FN

详细信息
    作者简介:

    李璐(1986—),女,主治医师,主要从事肝病研究

    通讯作者:

    陈煜, chybeyond1071@ccmu.edu.cn

  • 作者贡献声明:李璐、李爽负责查阅文献;李璐负责撰写文章;陈煜负责指导撰写、修改文章,并最后定稿。
  • 中图分类号: R575

Pathogenesis of coronavirus disease 2019 with liver injury

  • 摘要: 新型冠状病毒肺炎已对全球公共卫生造成了重大威胁。除呼吸系统外,部分患者可出现不同程度的肝损伤。基于相关文献,对病原学特征及其致病机制进行分析,初步探讨导致新型冠状病毒肺炎合并肝损伤出现的原因可能有病毒的直接作用、炎性细胞因子风暴、药物性肝损伤、低氧性肝损伤及免疫功能障碍等。建议临床可选择合理药物进行护肝治疗,减少肝损伤的发生。
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  • 收稿日期:  2020-07-04
  • 修回日期:  2020-07-30
  • 刊出日期:  2021-01-18
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