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局部枸橼酸抗凝在肝衰竭患者连续性肾脏替代治疗中的应用

金源源 诸炳骅 费雪洁 王倩

金源源, 诸炳骅, 费雪洁, 等. 局部枸橼酸抗凝在肝衰竭患者连续性肾脏替代治疗中的应用[J]. 临床肝胆病杂志, 2021, 37(1): 200-203. DOI: 10.3969/j.issn.1001-5256.2021.01.044
引用本文: 金源源, 诸炳骅, 费雪洁, 等. 局部枸橼酸抗凝在肝衰竭患者连续性肾脏替代治疗中的应用[J]. 临床肝胆病杂志, 2021, 37(1): 200-203. DOI: 10.3969/j.issn.1001-5256.2021.01.044
JIN YY, ZHU BH, FEI XJ, et al. Clinical application of regional citrate anticoagulation in continuous renal replacement therapy for patients with liver failure[J]. J Clin Hepatol, 2021, 37(1): 200-203. DOI: 10.3969/j.issn.1001-5256.2021.01.044
Citation: JIN YY, ZHU BH, FEI XJ, et al. Clinical application of regional citrate anticoagulation in continuous renal replacement therapy for patients with liver failure[J]. J Clin Hepatol, 2021, 37(1): 200-203. DOI: 10.3969/j.issn.1001-5256.2021.01.044

局部枸橼酸抗凝在肝衰竭患者连续性肾脏替代治疗中的应用

DOI: 10.3969/j.issn.1001-5256.2021.01.044
基金项目: 

上海申康医院发展中心临床科技创新项目 SHDC12017X23

详细信息
    作者简介:

    金源源(1994—),女,主要从事中西医结合治疗危重症的研究

    通讯作者:

    王倩,3202369986@qq.com

  • 作者贡献声明:金源源拟定写作思路,查阅文献资料,撰写文章;诸炳骅、费雪洁指导写作思路,指导撰写文章; 王倩基金支持,修改文章并最后定稿。
  • 中图分类号: R575.3;R459.5

Clinical application of regional citrate anticoagulation in continuous renal replacement therapy for patients with liver failure

  • 摘要: 体外抗凝是连续性肾脏替代治疗(CRRT)的一项关键技术,肝素曾是CRRT首选的抗凝剂,但由于出血风险高,临床使用受限。枸橼酸作为一种新型局部抗凝剂,近年来受到越来越多的关注和推荐,但对于肝衰竭患者的应用一直存在争议。通过阅读近年来国内外相关文献,就局部枸橼酸抗凝在肝衰竭患者中的代谢特点、监测方法及其在CRRT应用中的安全性进行综述。
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  • 收稿日期:  2020-07-16
  • 修回日期:  2020-08-13
  • 刊出日期:  2021-01-18
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