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阻塞性睡眠呼吸暂停对非酒精性脂肪性肝病的影响

许青青 唐海英 毛靖伟

许青青, 唐海英, 毛靖伟. 阻塞性睡眠呼吸暂停对非酒精性脂肪性肝病的影响[J]. 临床肝胆病杂志, 2021, 37(1): 192-195. DOI: 10.3969/j.issn.1001-5256.2021.01.042
引用本文: 许青青, 唐海英, 毛靖伟. 阻塞性睡眠呼吸暂停对非酒精性脂肪性肝病的影响[J]. 临床肝胆病杂志, 2021, 37(1): 192-195. DOI: 10.3969/j.issn.1001-5256.2021.01.042
XU QQ, TANG HY, MAO JW. Impact of obstructive sleep apnea on nonalcoholic fatty liver disease [J]. J Clin Hepatol, 2021, 37(1): 192-195. DOI: 10.3969/j.issn.1001-5256.2021.01.042
Citation: XU QQ, TANG HY, MAO JW. Impact of obstructive sleep apnea on nonalcoholic fatty liver disease [J]. J Clin Hepatol, 2021, 37(1): 192-195. DOI: 10.3969/j.issn.1001-5256.2021.01.042

阻塞性睡眠呼吸暂停对非酒精性脂肪性肝病的影响

DOI: 10.3969/j.issn.1001-5256.2021.01.042
基金项目: 

国家自然科学基金资助项目 81500402

详细信息
    作者简介:

    许青青(1993—),女,主要从事非酒精性脂肪性肝病临床及基础研

    通讯作者:

    毛靖伟,jingweimao@163.com

  • 作者贡献声明:许青青负责资料分析,撰写论文;唐海英参与资料分析,修改论文;毛靖伟负责拟定写作思路,指导撰写文章并最后定稿。
  • 中图分类号: R575.5; R56

Impact of obstructive sleep apnea on nonalcoholic fatty liver disease

  • 摘要: 阻塞性睡眠呼吸暂停(OSA)引起机体长期处于慢性间歇性缺氧可导致多系统、多器官病变,严重者可发生心源性猝死。除合并呼吸、心脑血管、内分泌代谢等疾病外,OSA与消化系统疾病中的非酒精性脂肪性肝病(NAFLD)也有密切关联。简述了OSA和NAFLD的现状,叙述了OSA对NAFLD的影响,归纳了OSA影响NAFLD的机制,提出通过探索OSA影响NAFLD的可能机制,从OSA角度为NAFLD寻找新的潜在防治靶点,对延缓、甚至阻断NAFLD进展具有重要意义。
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  • 收稿日期:  2020-07-06
  • 修回日期:  2020-08-26
  • 刊出日期:  2021-01-18
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