阿帕替尼联合经肝动脉化疗栓塞术治疗肝细胞癌的研究进展

朱泽民; 赵志坚; 唐才喜

doi:10.3969/j.issn.1001-5256.2020.10.036

阿帕替尼联合经肝动脉化疗栓塞术治疗肝细胞癌的研究进展

DOI: 10.3969/j.issn.1001-5256.2020.10.036

中南大学湘雅医学院附属株洲医院肝胆胰脾外科

基金项目:

湖南省科技计划项目经费资助(2016SK4006)；

详细信息

中图分类号: R735.7
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- 文章访问数: 459
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- 被引次数: 0
出版历程
- 收稿日期: 2020-04-17
- 出版日期: 2020-10-20

Research advances in apatinib combined with transcatheter arterial embolization in the treatment of hepatocellular carcinoma

Department of Hepatobiliary and Pancreatosplenic Surgery,Zhuzhou Hospital Affiliated to Xiangya School of Medicine,Central South University

Research funding:

摘要

摘要: 肝细胞癌是一种威胁全人类健康的常见恶性肿瘤,其发病率和病死率不断上升。大多数肝细胞癌患者确诊时已为中晚期,无法接受潜在的治疗性手术。经肝动脉化疗栓塞术(TACE)和抗血管生成药物阿帕替尼是治疗肝细胞癌的两种姑息治疗方法。目前,阿帕替尼联合TACE的应用在临床中治疗肝细胞癌仍然是一种新的治疗方法,有关其临床疗效和安全性目前尚存在争议,需进一步研究。综述了阿帕替尼联合TACE治疗肝细胞癌的研究进展。
- 癌,肝细胞 /
- 化学栓塞,治疗性 /
- 阿帕替尼
Abstract: Hepatocellular carcinoma( HCC) is a common malignant tumor that threatens the health of all mankind,and its incidence and mortality rates keep increasing in recent years. Most patients are in the advanced stage at the time of confirmed diagnosis and are unable to undergo potential therapeutic surgery. Transcatheter arterial chemoembolization( TACE) and the anti-angiogenic drug apatinib are two palliative treatments for HCC. At present,apatinib combined with TACE is still a new treatment method for HCC in clinical practice,and there are still controversies over its efficacy and safety,which needs further studies. This article reviews the research advances in apatinib combined with TACE in the treatment of HCC.
- carcinoma,hepatocellar /
- chemoembolization,therapeutic /
- apatinib

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参考文献(34)

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