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浸润胆囊伴双侧睾丸转移右半结肠腺癌1例报告

鲁香凤 荆涛 秦伟娜 张书信 戴欣

引用本文:
Citation:

浸润胆囊伴双侧睾丸转移右半结肠腺癌1例报告

DOI: 10.3969/j.issn.1001-5256.2020.10.029
详细信息
  • 中图分类号: R735.35

A case of right-sided colon adenocarcinoma with gallbladder invasion and bilateral testicular metastasis

  • 摘要: <正>1病例资料患者男性,69岁,因"右上腹疼痛反复发作伴腹胀"于2015年11月18日入本院,既往史:20年前因外伤脾破裂行脾切除术;否认肝炎、结核等传染病史,无吸烟饮酒嗜好,无家族遗传病史;患者又诉右侧阴囊部坠胀疼痛,体质量减轻1个月,查体:右上腹轻压痛,无反跳痛,胆囊未触及,Murphy征阳性;腹部未触及肿块,左上腹可见一长约7 cm手术瘢痕;右侧阴囊触痛明显,睾丸体积明显增大,质硬,边缘尚光滑,睾丸与附睾界限不清,无压痛; B超示胆囊炎、胆石症;中下腹CT示:升结肠的平脐部可见环形增厚,考虑升结肠癌;结肠镜示:升结肠中段环形肿物,表面呈菜花样,质脆易出血;血清CA19-9、CEA及CA72-4升高,前列腺特异抗原(PSA)正常;彩超示:右侧睾丸内实性结节,结构不清晰,右侧阴囊内实性肿物,血流信号丰富;肝肺未发现异常,分别行胆囊、右半结肠、右侧睾丸及附睾、

     

  • [1] TANG HJ,HUANG W,WU SL,et al. Gallbladder metastasis of colon cancer:A case report[J]. Guangdong Med J,2014,35(18):2926.(in Chinese)汤慧君,黄卫,吴胜兰,等.结肠癌胆囊转移1例[J].广东医学,2014,35(18):2926.
    [2] DONG SF,JIN J,CHI H,et al. A case of metastasis of testis and epididymis after colorectal cancer operation[J]. J Clin Urol,2005,20(10):605.(in Chinese)董圣芳,金键,迟辉,等.结肠癌术后并睾丸附睾转移癌1例[J].临床泌尿外科杂志,2005,20(10):605.
    [3] OUELLETTE JR,HARBOE-SCHMIDT JE,LUTHRINGER D,et al. Colorectal cancer metastasis presenting as a testicular mass:Case report and review of the literature[J]. Am Surg,2007,73(1):79-81.
    [4] LIU TH. Diagnostic pathology[M]. Third edition. Beijing:People’s Medical Publishing House,2014:78.(in Chinese)刘彤华.诊断病理学[M].第3版.北京:人民卫生出版社,2014:78.
    [5] CHEN CX,MA H,ZHAN SH. Differences in microsatellite instability,K-ras gene mutation and other clinicopathological features between right and left hemicolon cancer[J]. Chin J Gastroenterol,2019,24(7):400-405.(in Chinese)陈朝旭,马欢,战淑慧.左、右半结肠癌在微卫星不稳定性、Kras基因突变以及其他临床病理特征方面的差异[J].胃肠病学,2019,24(7):400-405.
    [6] Peoples’s Republic of China Health and Family Planning Commission of medical affairs authority,Chinese Medical Association Oncology Society. Chinese standard for diagnosis and treatment of colorectal cancer(2015 Edition)[J/CD]. Chin Arch Gen Surg(Electronic Edition),2015,9(6):506-523.(in Chinese)中华人民共和国卫生和计划生育委员会医政医管局,中华医学会肿瘤学会分会.中国结直肠癌诊疗规范(2015版)[J/CD].中华普通外科学文献(电子版),2015,9(6):506-523.
    [7] AMIN MB. Tumours of collecting duct and rete testis[M]//Holger Moch,Peter A. Humphrey,Thomas M. Ulbright,et al.WHO classification of the tumours of urinary system and male genital organs. 4thedition, IARC 69372 Lyon Cedex 08,France,2019:244-245.
    [8] ARISAN S,AKBULUT ON,CAKIR OO,et al. Primary adenocarcinoma of the epididymis:Case report[J]. Int Urol Nephrol,2004,36(1):77-80.
    [9] JONES MA,YOUNG RH,SCULLY RE. Adenocarcinoma of the epididymis:A report of four cases and review of the literature[J]. Am J Surg Pathol,1997,21(12):1474-1480.
    [10] WANG WM,DONG L,LI WB,et al. Screening strategy for Lynch syndrome associated colorectal cancer through genetic and molecular pathology technique[J/CD]. Chin J Colorectal Dis,2018,7(2):176-180.(in Chinese)王雯邈,董林,李文斌,等.Lynch syndrome相关结直肠癌的遗传基因及分子病理筛查策略[J/CD].中华结直肠疾病电子杂志,2018,7(2):176-180.
    [11] PENG WM,HUANG RM,ZHENG XL,et al. Clinicopathological analysis of 17 cases of colorectal cancer metastasis to ovary[J]. J Clin Exp Pathol,1995,11(4):333.(in Chinese)彭文明,黄锐明,郑秀玲,等.大肠癌转移卵巢17例临床病理分析[J].临床与实验病理学杂志,1995,11(4):333.
    [12] WU M,LUO WX,CUI XH,et al. Cervical metastasis of colon cancer:A case report[J]. Mil Med J Southeast China,2012,14(1):26,35.(in Chinese)吴曼,骆文香,崔向华,等.结肠癌宫颈转移1例[J].东南国防医药,2012,14(1):26,35.
    [13] ZHOU XY,LI D,FANG Y,et al. Scrotal metastasis of colon cancer:A case report[J]. China Oncol,2012,22(7):554-555.(in Chinese)周小芸,李达,方勇,等.结肠癌阴囊转移1例报道[J].中国癌症杂志,2012,22(7):554-555.
    [14] WANG ZZ,LI QY,YUAN XB. A case of splenic metastasis of cecal adenocarcinoma[J]. Sinohydro Medicine,2005,(2):96-97.(in Chinese)王梓桢,李秋阳,袁孝宾.盲肠腺癌脾转移1例[J].中国水电医学,2005,(2):96-97.
    [15] QIAN LH,HUI YZ. Liver non-tumor diseases,tumor and tumor-like diseases[M]//ZHENG J. Surgical pathology:Volume I. Peking University Medical Press,2014:965.(in Chinese)钱利华,回允中.肝非肿瘤性疾病、肿瘤和肿瘤样疾病[M]//郑杰主译.外科病理学:上卷.北京大学医学出版社,2014:965.
    [16] PARK JH,KIM MJ,PARK SC,et al. Difference in time to locoregional recurrence between patients with right-sided and left-sided colon cancers[J]. Dis Colon Rectum,2015,58(9):831-837.
    [17] LI XY,QU YF,LI J,et al. Variations in clinical characteristic and prognosis of colon carcinoma by location[J]. Acad J Chinese PLA Postgrad Med Sch,2016,37(11):1142-1144,1196.(in Chinese)李昕雨,屈怡帆,李娟,等.不同发病部位结肠癌临床特征及预后分析[J].解放军医学院学报,2016,37(11):1142-1144,1196.
    [18] ZHANG YY,LI PY,CAI YW,et al. Clinicopathological features of colorectal carcinoma patients with synchronous and metachronous metastasis[J]. J Clin Pathol Res,2017,37(7):1387-1392.(in Chinese)张嫄怡,李品玉,蔡悦炜,等.结直肠癌同时及异时性远处转移的临床病理学特征[J].临床与病理杂志,2017,37(7):1387-1392.
    [19] YAHAGI M,OKABAYASHI K,HASEGAWA H,et al. The worse prognosis of right-sided compared with left-sided colon cancers:A systematic review and Meta-analysis[J]. J Gastrointest Surg,2016,20(3):648-655.
    [20] ZHANG GY,CAO F,SHI L,et al. Clinical characteristics and prognosis of right and left colon cancer with bone metastasis[J]. Mod Oncol,2019,27(9):1581-1584.(in Chinese)张国耀,曹非,史磊,等.左、右半结肠癌骨转移临床特征及生存分析[J].现代肿瘤医学,2019,27(9):1581-1584.
    [21] SHEN H,YANG J,HUANG Q,et al. Different treatment strategies and molecular features between right-sided and leftsided colon cancers[J]. World J Gastroenterol,2015,21(21):6470-6478.
    [22] HU XR,XU C,KANG Y,et al. Correlation between mismatchrepair protein expression and clinicopathological features in 658colorectal cancers[J]. Chin J Pathol,2018,47(11):827-833.(in Chinese)胡晓儒,徐灿,亢野,等.658例结直肠癌错配修复蛋白的表达及其与临床病理特征的关系[J].中华病理学杂志,2018,47(11):827-833.
    [23] GAO J,SUN ZW,LI YY,et al. Mutations of KRAS and BRAF in Chinese patients with colorectal carcinoma:Analyses of 966 cases[J]. Chin J Pathol,2012,41(9):579-583.(in Chinese)高静,孙志伟,李艳艳,等.中国结直肠癌患者966例中KRAS和BRAF基因突变分析[J].中华病理学杂志,2012,41(9):579-583.
    [24] LIU XN,TIAN Z,WEI XF,et al. Combined detection of KRAS,NRAS,BRAF and PIK3CA mutation in the plasma and tumor tissues of colorectal cancer patients[J]. Chin J Pathol,2019,48(5):373-377.(in Chinese)刘晓娜,田庄,魏晓飞,等.联合检测结直肠癌患者血浆及组织中KRAS、NRAS、BRAF及PIK3CA基因突变情况[J].中华病理学杂志,2019,48(5):373-377.
    [25] SUGAI T,HABANO W,JIAO YF,et al. Analysis of molecular alterations in left-and right-sided colorectal carcinomas reveals distinct pathways of carcinogenesis:Proposal for new molecular profile of colorectal carcinomas[J]. J Mol Diagn,2006,8(2):193-201.
    [26] KOESTLER DC,LI J,BARON JA,et al. Distinct patterns of DNA methylation in conventional adenomas involving the right and left colon[J]. Mod Pathol,2014,27(1):145-155.
    [27] YOKOTA T,URA T,SHIBATA N,et al. BRAF mutation is a powerful prognostic factor in advanced and recurrent colorectal cancer[J]. Br J Cancer,2011,104(5):856-862.
    [28] KOSTAKIS ID,AGROGIANNIS G,VAIOPOULOS AG,et al.KISS1 expression in colorectal cancer[J]. APMIS,2013,121(10):1004-1010.
    [29] XU KY,LIAN ZJ,WU JP,et al. Differential expression of MMP-3 mRNA in left-sided and right-sided colon cancer and its relationships with clinicolpathological parameters and prognosis[J].Shandong Med,2016,56(24):1-4.(in Chinese)许开宇,连正杰,伍江平,等.MMP-3 mRNA在左、右半结肠癌组织中的表达及其与患者临床病理参数和预后的关系[J].山东医药,2016,56(24):1-4.
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