microRNA在原发性胆汁性胆管炎发病机制、诊断和疗效评估中的作用

王静; 张碧擎; 潘韵芝; 朱传武

doi:10.3969/j.issn.1001-5256.2019.07.047

microRNA在原发性胆汁性胆管炎发病机制、诊断和疗效评估中的作用

DOI: 10.3969/j.issn.1001-5256.2019.07.047

苏州大学附属第三医院 a.感染性疾病科; b.中医科
苏州市第五人民医院

详细信息

中图分类号: R575.7
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出版历程
- 收稿日期: 2019-01-08
- 出版日期: 2019-07-20

Role of microRNA in the pathogenesis, diagnosis, and outcome evaluation of primary biliary cholangitis

Department of Infectious Diseases, The Third Affiliated Hospital of Soochow University, Changzhou, Jiangsu 213003, China

摘要

摘要:
原发性胆汁性胆管炎(PBC)是一种常见的自身免疫性肝病之一,目前其发病机制仍不明确。归纳了microRNA在PBC发病机制及诊断、疗效评估中的作用,提示microRNA可能参与PBC的发生与发展过程,并可作为诊断和评估疗效的潜在生物标志物。
- 微RNAs /
- 原发性胆汁性胆管炎 /
- 病理过程 /
- 诊断 /
- 治疗学
Abstract:
Primary biliary cholangitis ( PBC) is one of common autoimmune liver diseases, and its pathogenesis remains unclear. This article summarizes the role of microRNA in the pathogenesis, diagnosis, and outcome evaluation of PBC and points out that microRNA may be involved in the development and progression of PBC and may thus be used as a potential biomarker for diagnosis and outcome evaluation.
- microRNAs /
- primary biliary cholangitis /
- pathologic processes /
- diagnosis /
- therapeutics

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