肝(窦)前型非肝硬化门静脉高压症的诊断与治疗及其面临的困境

徐航飞; 丁惠国

doi:10.3969/j.issn.1001-5256.2019.01.002

肝(窦)前型非肝硬化门静脉高压症的诊断与治疗及其面临的困境

DOI: 10.3969/j.issn.1001-5256.2019.01.002

首都医科大学附属北京佑安医院肝病消化中心

基金项目:

北京市医院管理局扬帆计划(ZYLX201610)；登峰计划(DFL20151602)；

详细信息

中图分类号: R575.2
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- 文章访问数: 465
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- 被引次数: 0
出版历程
- 收稿日期: 2018-11-16
- 出版日期: 2019-01-20

Diagnosis and treatment of pre-hepatic (sinusoidal) non-cirrhotic portal hypertension and related difficulties

Center of Hepatic and Digestive Diseases, Beijing YouAn Hospital, Capital Medical University

Research funding:

摘要

摘要: 肝(窦)前型非肝硬化性门静脉高压症(NCPH)是一组以门静脉高压症为突出表现的血管异质性疾病,病因复杂。与肝硬化门静脉高压症相比,NCPH患者肝功能基本正常,肝静脉压力梯度正常或轻度增加,预后较好,极易误诊为不明原因肝硬化门静脉高压症,肝脏病理是诊断"金标准"。目前,非选择性β受体阻滞剂及内镜是NCPH的主要治疗方法,但是缺乏前瞻性多中心、大样本、高质量的临床证据。
- 高血压,门静脉 /
- 诊断 /
- 治疗
Abstract: Pre-hepatic (sinusoidal) non-cirrhotic portal hypertension is a group of vascular heterogeneous diseases with portal hypertension as the prominent manifestation and has a complex etiology.Compared with the patients with cirrhotic portal hypertension, the patients with prehepatic (sinusoidal) non-cirrhotic portal hypertension have normal liver functions, normal or a mild increase in hepatic venous pressure gradient, and better prognosis.Pre-hepatic (sinusoidal) non-cirrhotic portal hypertension may easily be misdiagnosed as unexplained cirrhotic portal hypertension, and liver pathology is the gold standard for diagnosis.Non-selectiveβ-receptor blockers and endoscopy are major therapies for this disease, but there is a lack of high-quality clinical evidence from large-scale prospective multicenter studies.
- hypertension, portal /
- diagnosis /
- therapy

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参考文献(27)

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