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隐匿性胆总管结石诊断与治疗的新进展

王超 徐锋 刘晓琳 戴朝六

引用本文:
Citation:

隐匿性胆总管结石诊断与治疗的新进展

DOI: 10.3969/j.issn.1001-5256.2017.07.042
详细信息
  • 中图分类号: R575.7

Latest advances in diagnosis and treatment of occult common bile duct stones

  • 摘要: 隐匿性胆总管结石临床上无症状,如不及时诊断和处理,可诱发胆囊切除术后不明原因腹痛,或是胆源性胰腺炎、急性胆管炎等严重并发症而危及生命。选择合适的诊断及治疗方式可降低术后并发症、节约医疗资源并可能减少医患纠纷。简述了隐匿性胆总管结石的诊断与治疗新进展,包括影像学检查(腹部超声、CT、磁共振胰胆管造影、超声内镜、经内镜逆行胰胆管造影、术中胆道造影、术中腹腔镜超声、胆管腔内超声及术中胆道镜)的基本特点和诊断效能,不同治疗方式(十二指肠乳头括约肌切开术、腹腔镜胆总管探查术、开腹胆总管探查、内镜下球囊扩张术、液电碎石法、体外冲击波碎石法、结石溶解法及激光碎石法)的治疗效果。指出隐匿性胆总管结石的诊疗应根据风险分层区别对待。中层以上风险者应尽可能完善超声内镜或磁共振胰胆管造影检查,其结果对术式的选择至关重要。治疗方式上应根据实际条件酌情选择腹腔镜胆总管探查术或经内镜逆行胰胆管造影/十二指肠乳头括约肌切开术。

     

  • [1]DEBRAY D, FRANCHI-ABELLA S, IRTAN S, et al.Cholelithiasis in infants, children and adolescents[J].Presse Med, 2012, 41 (5) :466-473.
    [2]DENG XM, YANG X, CHEN Y, et al.Minimally invasive therapy for occult choledocholithiasis during laparoscopic cholecystectomy[J].Chin J Min Inv Surg, 2014, 14 (9) :796-798. (in Chinese) 邓小明, 杨星, 陈焱, 等.腹腔镜胆囊切除术中隐匿性胆总管结石的微创治疗[J].中国微创外科杂志, 2014, 14 (9) :796-798.
    [3]MAPLE JT, BEN-MENACHEM T, ANDERSON MA, et al.The role of endoscopy in the evaluation of suspected choledocholithiasis[J].Gastrointest Endosc, 2010, 71 (1) :1-9.
    [4]PENG WK, SHEIKH Z, PATERSON-BROWN S, et al.Role of liver function tests in predicting common bile duct stones in acute calculous cholecystitis[J].Br J Surg, 2005, 92 (10) :1241-1247.
    [5]GIANNINI EG, TESTA R, SAVARINO V.Liver enzyme alteration:a guide for clinicians[J].CMAJ, 2005, 172 (3) :367-379.
    [6]ISHERWOOD J, GARCEA G, WILLIAMS R, et al.Serology and ultrasound for diagnosis of choledocholithiasis[J].Ann R Coll Surg Engl, 2014, 96 (3) :224-228.
    [7]GURUSAMY KS, GILJACA V, TAKWOINGI Y, et al.Ultrasound versus liver function tests for diagnosis of common bile duct stones[J].Cochrane Database Syst Rev, 2015, 2:CD011548.
    [8]ZHANG H, HUANG P, ZHANG XF, et al.Comparison of endoscopic ultrasonography, transabdominal ultrasonography and magnetic resonance cholangiopancreatography in diagnosis of common bile duct stones[J].Chin J Endosc, 2015, 21 (1) :26-29. (in Chinese) 张皞, 黄平, 张筱凤, 等.超声内镜、腹部超声及磁共振胰胆管造影对胆总管结石诊断价值的对比分析研究[J].中国内镜杂志, 2015, 21 (1) :26-29.
    [9]TSENG CW, CHEN CC, CHEN TS, et al.Can computed tomography with coronal reconstruction improve the diagnosis of choledocholithiasis?[J].J Gastroenterol Hepatol, 2008, 23 (10) :1586-1589.
    [10]KONDO S, ISAYAMA H, AKAHANE M, et al.Detection of common bile duct stones:comparison between endoscopic ultrasonography, magnetic resonance cholangiography, and helical-computed-tomographic cholangiography[J].Eur J Radiol, 2005, 54 (2) :271-275.
    [11]LEE JK, KIM TK, BYUN JH, et al.Diagnosis of intrahepatic and common duct stones:combined unenhanced and contrast-enhanced helical CT in 1090 patients[J].Abdom Imaging, 2006, 31 (4) :425-432.
    [12]WU F, WANG C, JIANG SS, et al.Contrast research of different imaging diagnostic methods on choledocholithiasis[J].J Med Imaging, 2012, 22 (7) :1140-1145. (in Chinese) 吴非, 王翠, 姜书山, 等.不同影像检查方法诊断胆总管结石的比较研究[J].医学影像学杂志, 2012, 22 (7) :1140-1145.
    [13]CHEN GP.Value of plain CT scan in diagnosis of gallstones:an analysis of 131 cases[J].Guizhou Med J, 2014, 38 (1) :75-76. (in Chinese) 陈贵平.CT平扫诊断胆结石症131例分析[J].贵州医药, 2014, 38 (1) :75-76.
    [14]ZHOU ZW.The use value of multi-slice spiral computed tomography curved planar reformation technique in the diagnosis of clinical common bile duct expansion[J].J Hepatobiliary Surg, 2016, 24 (4) :282-284, 297. (in Chinese) 周占文.多层螺旋CT曲面重建技术在临床胆总管扩张诊断中的使用价值分析[J].肝胆外科杂志, 2016, 24 (4) :282-284, 297.
    [15]POLISTINA FA, FREGO M, BISELLO M, et al.Accuracy of magnetic resonance cholangiography compared to operative endoscopy in detecting biliary stones, a single center experience and review of literature[J].World J Radiol, 2015, 7 (4) :70-78.
    [16]CHEN W, MO JJ, LIN L, et al.Diagnostic value of magnetic resonance cholangiopancreatography in choledocholithiasis[J].World JGastroenterol, 2015, 21 (11) :3351-3360.
    [17]BILGIN M, TOPRAK H, BURGAZLI M, et al.Diagnostic value of dynamic contrast-enhanced magnetic resonance imaging in the evaluation of the biliary obstruction[J].Scientific World J, 2012, 2012:731089.
    [18]CHOI IY, YEOM SK, CHA SH, et al.Diagnosis of biliary stone disease:T1-weighted magnetic resonance cholangiography with Gd-EOB-DTPA versus T2-weighted magnetic resonance cholangiography[J].Clin Imaging, 2014, 38 (2) :164-169.
    [19]JIA L, GUO YN, GUO XL, et al.Value of endoscopic ultrasound and magnetic resonance cholangiopancreatography in diagnosis of obstructive jaundice[J].J Clin Hepatol, 2016, 32 (9) :1753-1755. (in Chinese) 贾雷, 郭玉宁, 郭秀丽, 等.超声内镜与磁共振胰胆管造影诊断梗阻性黄疸的效果比较[J].临床肝胆病杂志, 2016, 32 (9) :1753-1755.
    [20]GILJACA V, GURUSAMY KS, TAKWOINGI Y, et al.Endoscopic ultrasound versus magnetic resonance cholangiopancreatography for common bile duct stones[J].Cochrane Database Syst Rev, 2015, 2:CD011549.
    [21]LIN LF, HUANG PT.Linear endoscopic ultrasound for clinically suspected bile duct stones[J].J Chin Med Assoc, 2012, 75 (6) :251-254.
    [22]PETROV MS, SAVIDES TJ.Systematic review of endoscopic ultrasonography versus endoscopic retrograde cholangiopancreatography for suspected choledocholithiasis[J].Br J Surg, 2009, 96 (9) :967-974.
    [23]CHAN HH, WANG EM, SUN MS, et al.Linear echoendoscopeguided ERCP for the diagnosis of occult common bile duct stones[J].BMC Gastroenterol, 2013, 13:44.
    [24]GURUSAMY KS, GILJACA V, TAKWOINGI Y, et al.Endoscopic retrograde cholangiopancreatography versus intraoperative cholangiography for diagnosis of common bile duct stones[J].Cochrane Database Syst Rev, 2015, 2:CD010339.
    [25]ALMADI MA, BARKUN JS, BARKUN AN.Management of suspected stones in the common bile duct[J].CMAJ, 2012, 184 (8) :884-892.
    [26]VERMA S, WICHMANN MW, GUNNING T, et al.Intraoperative cholangiogram during laparoscopic cholecystectomy:a clinical trial in rural setting[J].Aust J Rural Health, 2016, 24 (6) :415-421.
    [27]MAH D, WALES P, NJERE I, et al.Management of suspected common bile duct stones in children:role of selective intraoperative cholangiogram and endoscopic retrograde cholangiopancreatography[J].J Pediatr Surg, 2004, 39 (6) :808-812.
    [28]JAMAL KN, SMITH H, RATNASINGHAM K, et al.Meta-analysis of the diagnostic accuracy of laparoscopic ultrasonography and intraoperative cholangiography in detection of common bile duct stones[J].Ann R Coll Surg Engl, 2016, 98 (4) :244-249.
    [29]TIAN H, LIU JF.The application of laparoscopic ultrasonography in difficult laparoscopic cholecystectomy[J].J Laparoscopic Surg, 2010, 15 (3) :207-209. (in Chinese) 田虎, 刘竞芳.腹腔镜超声在困难腹腔镜胆囊切除术中的应用[J].腹腔镜外科杂志, 2010, 15 (3) :207-209.
    [30]LI JW, FENG B, WU L, et al.Intraoperative cholangiography in combination with laparoscopic ultrasonography for the detection of occult choledocholithiasis[J].Med Sci Monit, 2009, 15 (9) :Mt126-130.
    [31]PARK SY, PARK CH, LIM SU, et al.Intraductal US-directed management of bile duct stones without radiocontrast cholangiography[J].Gastrointest Endosc, 2015, 82 (5) :939-943.
    [32]KIM DC, MOON JH, CHOI HJ, et al.Usefulness of intraductal ultrasonography in icteric patients with highly suspected choledocholithiasis showing normal endoscopic retrograde cholangiopancreatography[J].Dig Dis Sci, 2014, 59 (8) :1902-1908.
    [33]TIAN DG, ZHU H, ZHANG J, et al.Clinical application of fibercholedochoscopy treatment for patients with calculus of bile duct (report of 180 cases) [J].Chin J Bases Clin Gen Surg, 2004, 11 (6) :536-537. (in Chinese) 田大广, 朱洪, 张捷, 等.纤维胆道镜在治疗肝胆管结石中的临床应用 (附180例报告) [J].中国普外基础与临床杂志, 2004, 11 (6) :536-537.
    [34]ZHOU ZQ, FU ZH.Value of a combination of various endoscopic techniques in treatment of gallstones complicated by occult common bile duct stones:a clinical analysis of 47 cases[J].J Hepatopancreatobiliary Surg, 2015, 27 (5) :400-402. (in Chinese) 周宗庆, 傅志红.多镜联合治疗胆囊结石并隐匿性胆总管结石47例临床分析[J].肝胆胰外科杂志, 2015, 27 (5) :400-402.
    [35]WILLIAMS EJ, GREEN J, BECKINGHAM I, et al.Guidelines on the management of common bile duct stones (CBDS) [J].Gut, 2008, 57 (7) :1004-1021.
    [36]COLLINS C, MAGUIRE D, IRELAND A, et al.A prospective study of common bile duct calculi in patients undergoing laparoscopic cholecystectomy:natural history of choledocholithiasis revisited[J].Ann Surg, 2004, 239 (1) :28-33.
    [37]WANG C, TAO WY, XU W.Use of laparoscope combined with choledochoscope versus open surgical treatment of common bile duct calculi:a clinical comparative study[J].Chin J Gen Surg, 2013, 22 (2) :230-232. (in Chinese) 王晨, 陶文雅, 徐韦.腹腔镜联合胆道镜与开腹手术治疗胆总管结石临床对比研究[J].中国普通外科杂志, 2013, 22 (2) :230-232.
    [38]CHEN J, JU LT, YU L, et al.A comparative study of clinically therapeutic effect between laparoscopic combined with choledochoscopic choledocholithotomy and laparotomy in common bile duct exploration[J].J Laparoscopic Surg, 2010, 15 (7) :545-547. (in Chinese) 陈骏, 居来提, 于亮, 等.腹腔镜胆道镜胆总管探查取石术与开腹手术临床疗效比较[J].腹腔镜外科杂志, 2010, 15 (7) :545-547.
    [39]CHENG LM, LIU Y, SUN ZD, et al.Clinical effects of laparoscopy combined with choledochoscopy vs open surgery for common bile duct stones[J].World Chin J Dig, 2014, 22 (36) :5699-5702. (in Chinese) 程利民, 刘洋, 孙志德, 等.腹腔镜联合胆道镜与传统开腹手术治疗胆总管结石的临床疗效对比[J].世界华人消化杂志, 2014, 22 (36) :5699-5702.
    [40]KHARBUTLI B, VELANOVICH V.Management of preoperatively suspected choledocholithiasis:a decision analysis[J].J Gastrointest Surg, 2008, 12 (11) :1973-1980.
    [41]Internal Clinical Guidelines T, ‘National Institute for Health and Care Excellence:Clinical Guidelines’, in Gallstone Disease:Diagnosis and Management of Cholelithiasis, Cholecystitis and Choledocholithiasis[C].London:National Institute for Health and Care Excellence (UK) Copyright (c) National Clinical Guideline Centre, 2014, 2014.
    [42]ZHU HY, XU M, SHEN HJ, et al.A meta-analysis of single-stage versus two-stage management for concomitant gallstones and common bile duct stones[J].Clin Res Hepatol Gastroenterol, 2015, 39 (5) :584-593.
    [43]CHANG L, LO S, STABILE BE, et al.Preoperative versus postoperative endoscopic retrograde cholangiopancreatography in mild to moderate gallstone pancreatitis:a prospective randomized trial[J].Ann Surg, 2000, 231 (1) :82-87.
    [44]TIAN KL, ZHU LX, XIE K, et al.Laparoscopic cholecystectomy combined with endoscopic retrograde cholangiopancreatography vs laparoscopic common bile duct exploration in the treatment of concomitant gallstones and common bile duct stones:a meta analysis[J].Chin J Pract Surg, 2013, 33 (10) :881-886. (in Chinese) 田开亮, 朱立新, 谢坤, 等.LC联合ERCP/LCBDE治疗胆囊结石-胆总管结石疗效Meta分析[J].中国实用外科杂志, 2013, 33 (10) :881-886.
    [45]ZHANG ZY, DU LX, ZHENG W, et al.Clinical comparative study of laparoscopic common bile duct exporation versus endoscopic sphincterotomy for choledocholithiasis[J].Chin J Gen Surg, 2015, 24 (8) :1088-1092. (in Chinese) 张智勇, 杜立学, 郑伟, 等.腹腔镜胆总管探查术与内镜下十二指肠乳头括约肌切开术治疗胆总管结石的临床对照研究[J].中国普通外科杂志, 2015, 24 (8) :1088-1092.
    [46]DING J, LI F, ZHU HY, et al.Endoscopic treatment of difficult extrahepatic bile duct stones, EPBD or EST:an anatomic view[J].World JGastrointest Endosc, 2015, 7 (3) :274-277.
    [47]DISARIO JA.Endoscopic balloon dilation of the sphincter of Oddi for stone extraction in the elderly:is the juice worth the squeeze?[J].Gastrointest Endosc, 2008, 68 (3) :483-486.
    [48]ZHANG ZM, YUAN HM, ZHANG C.Strategy of laparoscopy and choledochoscopy or duodenoscopy for the treatment of cholecystolithiasis combined with choledocholithiasis[J].Chin J Dig Surg, 2015, 14 (4) :280-283. (in Chinese) 张宗明, 苑海明, 张翀.双镜联合同期治疗胆囊结石合并胆总管结石的策略[J].中华消化外科杂志, 2015, 14 (4) :280-283.
    [49]FENG Q, HUANG Y, WANG K, et al.Laparoscopic transcystic common bile duct exploration:advantages over laparoscopic choledochotomy[J].PLo S One, 2016, 11 (9) :e0162885.
    [50]EBNER S, RECHNER J, BELLER S, et al.Laparoscopic management of common bile duct stones[J].Surg Endosc, 2004, 18 (5) :762-765.
    [51]HAN W, ZHANG ZT.Current application of laparoscopic trans-cystic common bill duct exploration[J].Chin J Pract Surg, 2009, 29 (1) :44-46. (in Chinese) 韩威, 张忠涛.腹腔镜下胆道镜经胆囊管胆总管探查取石技术应用现状[J].中国实用外科杂志, 2009, 29 (1) :44-46.
    [52]EL-GEIDIE AA.Is the use of T-tube necessary after laparoscopic choledochotomy?[J].J Gastrointest Surg, 2010, 14 (5) :844-848.
    [53]GRUBNIK VV, TKACHENKO AI, ILYASHENKO VV, et al.Laparoscopic common bile duct exploration versus open surgery:comparative prospective randomized trial[J].Surg Endosc, 2012, 26 (8) :2165-2171.
    [54]ALJEBREEN AM, ALHARBI OR, AZZAM N, et al.Efficacy of spyglass-guided electrohydraulic lithotripsy in difficult bile duct stones[J].Saudi J Gastroenterol, 2014, 20 (6) :366-370.
    [55]TANDAN M, REDDY DN.Extracorporeal shock wave lithotripsy for pancreatic and large common bile duct stones[J].World J Gastroenterol, 2011, 17 (39) :4365-4371.
    [56]KELLY E, WILLIAMS JD, ORGAN CH.A history of the dissolution of retained choledocholithiasis[J].Am J Surg, 2000, 180 (2) :86-98.
    [57]LIU F, JIN ZD, ZOU DW, et al.Efficacy and safety of endoscopic biliary lithotripsy using FREDDY laser with a radiopaque mark under fluoroscopic guidance[J].Endoscopy, 2011, 43 (10) :918-921.
    [58]SHOJAIEFARD A, ESMAEILZADEH M, GHAFOURI A, et al.Various techniques for the surgical treatment of common bile duct stones:a meta review[J].Gastroenterol Res Pract, 2009, 2009:840208.
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