Research advances in insulin-like growth factor-1 receptor in pancreatic cancer
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摘要: 胰岛素样生长因子(IGF)1受体(IGF-1R)广泛存在于多种类型的细胞表面,与肿瘤细胞的形成、发展密切相关,也为肿瘤的靶向治疗提供了新的方向。对IGF-1R在胰腺癌中的表达、发生、发展以及IGF-1R作为靶点治疗肿瘤的进展作一综述。Abstract: Insulin-like growth factor-1 receptor ( IGF-1R) widely exists in the surface of various types of cells and is closely associated with the formation and development of tumor cells. It also provides a new direction for the targeted therapy for tumors. This article reviews the expression, development, and progression of IGF-1R in pancreatic cancer and research advances in IGF-1R as a target for tumor treatment.
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Key words:
- receptor, IGF type 1 /
- pancreatic neoplasms /
- review
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