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代谢综合征与脂肪肝

范建高 颜士岩

引用本文:
Citation:

代谢综合征与脂肪肝

DOI: 10.3969/j.issn.1001-5256.2016.03.001
详细信息
  • 中图分类号: R575.5;R589

Metabolic syndrome and fatty liver

  • 摘要: 代谢综合征(MS)与慢性肝病特别是脂肪肝关系密切,两者并存时的临床特征及其发病机制、诊断、治疗等方面的研究众多但结果仍有争论。介绍了MS及其相关脂肪肝与酒精性肝病和慢性病毒性肝炎临床研究的最新进展及困境,旨在帮助临床医生提高MS和脂肪肝的处理能力,更好地为此类患者服务。

     

  • [1]WANG FS,FAN JG,ZHANG Z,et al.The global burden of liver disease:the major impact of China[J].Hepatology,2014,60(6):2099-2108.
    [2] FAN JG.Epidemiology of alcoholic and nonalcoholic fatty liver disease in China[J].J Gastroenterol Hepatol,2013,28(Suppl 1):11-17.
    [3] RINELLA ME.Nonalcoholic fatty liver disease:a systematic review[J].JAMA,2015,313(22):2263-2273.
    [4]BYRNE CD,TARGHER G.NAFLD:A multisystem disease[J].J Hepatol,2015,62(Suppl 1):s47-s65.
    [5]NASCIMBENI F,PAIS R,BELLENTANI S,et al.From NAFLD in clinical practice to answers from guidelines[J].J Hepatol,2013,59(4):859-871.
    [6]O'SHEA RS,DASARATHY S,Mc CULLOUGH AJ.Alcoholic liver disease.AASLD practice guideline[J].Hepatology,2010,105(1):307-328.
    [7]GU D,REYNOLDS K,WU X,et al.Prevalence of the metabolic syndrome and overweight among adults in China[J].Lancet,2005,365(9468):1398-1405.
    [8]FAN JG,PENG YD.Metabolic syndrome and non-alcoholic fatty liver disease:Asian definitions and Asian studies[J].Hepatobiliary Pancreat Dis Int,2007,6(6):572-578.
    [9]FAN JG,SAIBARA T,CHITTURI S,et al.What are the risk factors and settings for non-alcoholic fatty liver disease in Asia-Pacific?[J].J Gastroenterol Hepatol,2007,22(6):794-800.
    [10] XU C,YU CH,MA H,et al.Prevalence and risk factors for the development of nonalcoholic fatty liver disease in a nonobese Chinese population:the Zhejiang Zhenhai Study[J].Am J Gastroenterol,2013,108(8):1299-1304.
    [11]ALBELDAWI M,AGGARWAL A,MADHWAL S,et al.Cumulative risk of cardiovascular events after orthotopic liver transplantation[J].Liver Transpl,2012,18(3):370-375.
    [12]AGRAWAL S,DARUWALA C.Metabolic syndrome and hepatic resection:improving outcome[J].HPB(Oxford),2011,13(12):846-859.
    [13]FAN JG,CAI XB,LI L,et al.Alcohol consumption and metabolic syndrome among Shanghai adults:a randomized multistage stratified cluster sampling investigation[J].World J Gastroenterol,2008,14(15):2418-2424.
    [14]GUNJI T,MATSUHASHI N,SATO H,et al.Alcohol consumption is inversely correlated with insulin resistance,independent of metabolic syndrome factors and fatty liver diseases[J].J Clin Gastroenterol,2011,45(9):808-813.
    [15]KIM JH,KIM SY,JUNG ES,et al.Carotid intima-media thickness is increased not only in non-alcoholic fatty liver disease patients but also in alcoholic fatty liver patients[J].Digestion,2011,84(2):149-155.
    [16]BUGIANESI E,SALAMONE F,NEGRO F.The interaction of metabolic factors with HCV infection:does it matter?[J].J Hepatol,2012,56(Suppl 1):s56-s65.
    [17]ADINOLFI LE,RESTIVO L,ZAMPINO R,et al.Chronic HCV infection is a risk of atherosclerosis.Role of HCV and HCV-related steatosis[J].Atherosclerosis,2012,221(2):496-502.
    [18]FAN JG,CHITTURI S.Hepatitis B and fatty liver:causal or coincidental?[J].J Gastroenterol Hepatol,2008,23(5):779-782.
    [19]HSU CS,LIU CH,WANG CC,et al.Impact of hepatitis B virus infection on metabolic profiles and modifying factors[J].J Viral Hepat,2012,19(2):e48-e57.
    [20]WONG VW,WONG GL,CHU WC,et al.Hepatitis B virus infection and fatty liver in the general population[J].J Hepatol,2012,56(3):533-540.
    [21]SHI JP,FAN JG,WU R,et al.Prevalence and risk factors of hepatic steatosis and its impact on liver injury in Chinese patients with chronic hepatitis B infection[J].J Gastroenterol Hepatol.2008,23(9):1419-1425.
    [22]PAN Q,ZHANG RN,WANG YQ,et al.Linked polymorphisms of PNPLA3 confer susceptibility to nonalcoholic steatohepatitis and decreased viral load in chronic hepatitis B[J].World J Gastroenterol,2015,21(28):8605-8614.
    [23]DING WJ,WANG MM,WANG GS,et al.Thyroid function is associated with non-alcoholic fatty liver disease in chronic hepatitis B infected subjects[J].J Gastroenterol Hepatol,2015,30(12):1753-1758.
    [24]WANG MM,WANG GS,SHEN F,et al.Hepatic steatosis is highly prevalent in hepatitis B patients and negatively associated with virological factors[J].Dig Dis Sci,2014,59(10):2571-2579.
    [25] JIN X,CHEN YP,YANG YD,et al.Association between hepatic steatosis and entecavir treatment failure in Chinese patients with chronic hepatitis B[J].PLo S One,2012,7(3):e34198.
    [26]HSIANG JC,WONG GL,CHAN HL,et al.Metabolic syndrome delays HBe Ag seroclearance in Chinese patients with hepatitis B[J].Aliment Pharmacol Ther,2014,40(6):716-726.
    [27]ZHANG Z,PAN Q,DUAN XY,et al.Fatty liver reduces hepatitis B virus replication in a genotype B hepatitis B virus transgenic mice model.Fatty liver reduces hepatitis B virus replication in a genotype B hepatitis B virus transgenic mice model[J].J Gastroenterol Hepatol,2012,27(12):1858-1864.
    [28]ZHANG RN,PAN Q,ZHANG Z,et al.Saturated fatty acid inhibits viral replication in chronic HBV infection with nonalcoholic fatty liver disease by TLR4 mediated innate immune response[J].Hepat Mon,2015,15(5):e27909.
    [29]CHU CM,LIN DY,LIAW YF.Clinical and virological characteristics post HBs Ag seroclearance in hepatitis B virus carriers with hepatic steatosis versus those without[J].Dig Dis Sci,2013,58(1):275-281.
    [30]BORENA W,STROHMAIER S,LUKANOVA A,et al.Metabolic risk factors and primary liver cancer in a prospective study of 578,700 adults[J].Int J Cancer,2012,131(1):193-200.
    [31]LIN CW,LIN CC,MO LR,et al.Heavy alcohol consumption increases the incidence of hepatocellular carcinoma in hepatitis B virus-related cirrhosis[J].J Hepatol,2013,58(4):730-735.
    [32]WELZEL TM,GRAUBARD BI,ZEUZEM S,et al.Metabolic syndrome increases the risk of primary liver cancer in the United States:a study in the SEER-Medicare database[J].Hepatology,2011,54(2):463-471.
    [33]Asia-Pacific Working Party for Prevention of Hepatocellular Carcinoma.Prevention of hepatocellular carcinoma in non-viral related liver diseases[J].J Gastroenterol Hepatol,2009,25(4):712-719.
    [34]NOBILI V,CARTER-KENT C,FELDSTEIN AE.The role of lifestyle changes in the management of chronic liver disease[J].BMC Med,2011,9(1):70.
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  • 收稿日期:  2016-02-03
  • 出版日期:  2016-03-20
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