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药物性肝损伤发病机制的研究进展

许新 纪莉莎 芦琳琳 陈丽丽 辛永宁 宣世英

许新, 纪莉莎, 芦琳琳, 陈丽丽, 辛永宁, 宣世英. 药物性肝损伤发病机制的研究进展[J]. 临床肝胆病杂志, 2016, 32(2): 382-385. DOI: 10.3969/j.issn.1001-5256.2016.02.041
引用本文: 许新, 纪莉莎, 芦琳琳, 陈丽丽, 辛永宁, 宣世英. 药物性肝损伤发病机制的研究进展[J]. 临床肝胆病杂志, 2016, 32(2): 382-385. DOI: 10.3969/j.issn.1001-5256.2016.02.041
Xu Xin, Ji LiSha, Lu LinLin, Chen LiLi, Xin YongNing, Xuan ShiYing. Research advances in the pathogenesis of drug-induced liver injury[J]. J Clin Hepatol, 2016, 32(2): 382-385. DOI: 10.3969/j.issn.1001-5256.2016.02.041
Citation: Xu Xin, Ji LiSha, Lu LinLin, Chen LiLi, Xin YongNing, Xuan ShiYing. Research advances in the pathogenesis of drug-induced liver injury[J]. J Clin Hepatol, 2016, 32(2): 382-385. DOI: 10.3969/j.issn.1001-5256.2016.02.041

药物性肝损伤发病机制的研究进展

DOI: 10.3969/j.issn.1001-5256.2016.02.041
详细信息
  • 中图分类号: R575

Research advances in the pathogenesis of drug-induced liver injury

  • 摘要: 近年来,随着用药种类和不合理用药的日益增多,药物性肝损伤(DILI)发病率及病死率日益增高。DILI发病机制复杂,可能涉及药物的直接肝毒性作用、免疫介导性的肝损伤、线粒体损伤、胆道损伤等方面。探讨及了解其发病机制对预防及治疗DILI尤为重要。综述了DILI发病机制的研究进展。

     

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  • 收稿日期:  2015-06-19
  • 出版日期:  2016-02-20
  • 刊出日期:  2016-02-20
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