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生长抑素联合泮托拉唑治疗肝硬化合并上消化道出血的效果观察

高成广 谢峰 冯亚东

高成广, 谢峰, 冯亚东. 生长抑素联合泮托拉唑治疗肝硬化合并上消化道出血的效果观察[J]. 临床肝胆病杂志, 2016, 32(2): 284-287. DOI: 10.3969/j.issn.1001-5256.2016.02.017
引用本文: 高成广, 谢峰, 冯亚东. 生长抑素联合泮托拉唑治疗肝硬化合并上消化道出血的效果观察[J]. 临床肝胆病杂志, 2016, 32(2): 284-287. DOI: 10.3969/j.issn.1001-5256.2016.02.017
Gao ChengGuang, Xie Feng, Feng YaDong. Effect of somatostatin combined with pantoprazole in treatment of liver cirrhosis with upper gastrointestinal hemorrhage[J]. J Clin Hepatol, 2016, 32(2): 284-287. DOI: 10.3969/j.issn.1001-5256.2016.02.017
Citation: Gao ChengGuang, Xie Feng, Feng YaDong. Effect of somatostatin combined with pantoprazole in treatment of liver cirrhosis with upper gastrointestinal hemorrhage[J]. J Clin Hepatol, 2016, 32(2): 284-287. DOI: 10.3969/j.issn.1001-5256.2016.02.017

生长抑素联合泮托拉唑治疗肝硬化合并上消化道出血的效果观察

DOI: 10.3969/j.issn.1001-5256.2016.02.017
详细信息
  • 中图分类号: R575.2

Effect of somatostatin combined with pantoprazole in treatment of liver cirrhosis with upper gastrointestinal hemorrhage

  • 摘要: 目的评价生长抑素联合泮托拉唑治疗肝硬化合并上消化道出血的疗效。方法选取2011年1月-2015年8月泰州市姜堰中医院收治的肝硬化合并上消化道出血患者70例,随机分为两组,联合组与对照组各35例。两组患者入院后均给予常规基础治疗,联合组加用生长抑素联合泮托拉唑治疗,对照组予以生长抑素治疗。观察治疗前后两组临床疗效、止血时间、输血量、48 h再出血率、住院时间及不良反应。计量资料组间比较采用t检验,计数资料组间比较采用χ2检验,等级资料组间比较采用Wilcoxon秩和检验。结果联合组的临床疗效明显优于对照组,联合组总有效率94.3%,对照组总有效率62.9%,两组临床疗效差异有统计学意义(χ2=10.27,P<0.05),联合组显效率为60.0%,对照组显效率34.3%,两组显效率差异无统计学意义(χ2=2.80,P>0.05);在止血时间、输血量、住院时间方面,联合组明显低于对照组,两组比较差异均有统计学意义(t值分别为9.036、6.419、4.186,P值均<0.05);联合组48 h再出血率低于对照组,两组间差异无统计学意义(χ2=0.22,P>0.05);...

     

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  • 收稿日期:  2015-10-09
  • 出版日期:  2016-02-20
  • 刊出日期:  2016-02-20
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