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血清-腹水白蛋白梯度与肝硬化食管胃底静脉曲张破裂出血关系的Meta分析

张辉 徐有青

张辉, 徐有青. 血清-腹水白蛋白梯度与肝硬化食管胃底静脉曲张破裂出血关系的Meta分析[J]. 临床肝胆病杂志, 2016, 32(2): 269-274. DOI: 10.3969/j.issn.1001-5256.2016.02.014
引用本文: 张辉, 徐有青. 血清-腹水白蛋白梯度与肝硬化食管胃底静脉曲张破裂出血关系的Meta分析[J]. 临床肝胆病杂志, 2016, 32(2): 269-274. DOI: 10.3969/j.issn.1001-5256.2016.02.014
Zhang Hui, Xu YouQing. Association between serum ascites albumin gradient and esophagogastric variceal bleeding in patients with liver cirrhosis: a Meta-analysis[J]. J Clin Hepatol, 2016, 32(2): 269-274. DOI: 10.3969/j.issn.1001-5256.2016.02.014
Citation: Zhang Hui, Xu YouQing. Association between serum ascites albumin gradient and esophagogastric variceal bleeding in patients with liver cirrhosis: a Meta-analysis[J]. J Clin Hepatol, 2016, 32(2): 269-274. DOI: 10.3969/j.issn.1001-5256.2016.02.014

血清-腹水白蛋白梯度与肝硬化食管胃底静脉曲张破裂出血关系的Meta分析

DOI: 10.3969/j.issn.1001-5256.2016.02.014
详细信息
  • 中图分类号: R575.2

Association between serum ascites albumin gradient and esophagogastric variceal bleeding in patients with liver cirrhosis: a Meta-analysis

  • 摘要:

    目的探讨血清-腹水白蛋白梯度(SAAG)与肝硬化食管胃底静脉曲张破裂出血之间的关系。方法检索Pub Med、Embase、the Cochrane Library、万方、维普及CNKI数据库于2001年1月-2015年6月发表的所有有关SAAG与肝硬化食管胃底静脉曲张出血的中文文献,每篇文献均需设立出血组和未出血组。应用加强观察性流行病学研究报告质量为参考标准评价文献质量。合并各文献出血组和未出血组SAAG均数及标准差。采用Meta-Analyst软件计算每篇文献中出血组和未出血组SAAG标准化均值差(SMD)并进行Meta分析,多组间计数资料比较采用行×列χ2检验。结果共有13篇文献符合纳入标准。出血组SAAG为(22.54±4.69)g/L,未出血组SAAG为(15.91±4.20)g/L。异质性检验提示存在显著的异质性(Q=100.735,I2=89.065,P<0.001),出血组SAAG值显著高于未出血组,两组SAAG值差异有统计学意义(SMD=1.970,95%可信区间:1.4252.515,P<0.001)。根据SAAG水平分为SAAG&...

     

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  • 收稿日期:  2015-11-09
  • 出版日期:  2016-02-20
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