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非肝硬化性门静脉高压症的研究现状

张博静 韩国宏 樊代明

张博静, 韩国宏, 樊代明. 非肝硬化性门静脉高压症的研究现状[J]. 临床肝胆病杂志, 2016, 32(2): 245-249. DOI: 10.3969/j.issn.1001-5256.2016.02.009
引用本文: 张博静, 韩国宏, 樊代明. 非肝硬化性门静脉高压症的研究现状[J]. 临床肝胆病杂志, 2016, 32(2): 245-249. DOI: 10.3969/j.issn.1001-5256.2016.02.009
Zhang BoJing, Han GuoHong, Fan DaiMing. Research advances in non-cirrhotic portal hypertension[J]. J Clin Hepatol, 2016, 32(2): 245-249. DOI: 10.3969/j.issn.1001-5256.2016.02.009
Citation: Zhang BoJing, Han GuoHong, Fan DaiMing. Research advances in non-cirrhotic portal hypertension[J]. J Clin Hepatol, 2016, 32(2): 245-249. DOI: 10.3969/j.issn.1001-5256.2016.02.009

非肝硬化性门静脉高压症的研究现状

DOI: 10.3969/j.issn.1001-5256.2016.02.009
详细信息
  • 中图分类号: R657.34

Research advances in non-cirrhotic portal hypertension

  • 摘要: 肝硬化是门静脉高压的最常见原因,但仍有约20%的门静脉高压继发于非肝硬化因素,称为非肝硬化性门静脉高压症(NCPH),在发展中国家发病率较高。NCPH是一组异源性的肝脏血管疾病,临床上多见的是特发性门静脉高压(IPH)、肝外门静脉血管阻塞(EHPVO),以及布加综合征、先天性肝纤维化和结节再生性增生等少见病。此类患者常常具有门静脉高压的证据,如反复发生的静脉曲张出血和脾脏肿大,但肝功能保存尚好。目前尚无诊断NCPH的统一标准,对其诊断仍是一个挑战。临床上往往采用排除性诊断,必要时可行肝穿刺活组织检查来确诊。介绍了IPH和EHPVO的发病机制、病理表现、诊断方法及治疗策略的选择,若能有效控制上消化道出血,NCPH被认为是预后相对良好的一类疾病。

     

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  • 收稿日期:  2015-09-30
  • 出版日期:  2016-02-20
  • 刊出日期:  2016-02-20
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