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成簇的规律间隔短回文重复序列/Cas9系统在病毒领域的应用

郑庆芬 段钟平 李建生

郑庆芬, 段钟平, 李建生. 成簇的规律间隔短回文重复序列/Cas9系统在病毒领域的应用[J]. 临床肝胆病杂志, 2016, 32(1): 185-187. DOI: 10.3969/j.issn.1001-5256.2016.01.041
引用本文: 郑庆芬, 段钟平, 李建生. 成簇的规律间隔短回文重复序列/Cas9系统在病毒领域的应用[J]. 临床肝胆病杂志, 2016, 32(1): 185-187. DOI: 10.3969/j.issn.1001-5256.2016.01.041
Zheng QingFen, Duan ZhongPing, Li JianSheng. Application of CRISPR/Cas9 system in virus research[J]. J Clin Hepatol, 2016, 32(1): 185-187. DOI: 10.3969/j.issn.1001-5256.2016.01.041
Citation: Zheng QingFen, Duan ZhongPing, Li JianSheng. Application of CRISPR/Cas9 system in virus research[J]. J Clin Hepatol, 2016, 32(1): 185-187. DOI: 10.3969/j.issn.1001-5256.2016.01.041

成簇的规律间隔短回文重复序列/Cas9系统在病毒领域的应用

DOI: 10.3969/j.issn.1001-5256.2016.01.041
详细信息
  • 中图分类号: R373

Application of CRISPR/Cas9 system in virus research

  • 摘要: 目前成簇的规律间隔的短回文重复序列(CRISPR)/Cas9系统已经在很多物种及细胞中被广泛用来编辑基因组DNA,这一系统是第三代人工核酸内切酶,通过识别短的病毒序列来完成基因的编辑。介绍了该系统的结构特点以及在病毒领域的应用,包括病毒相关基因的功能研究,以及抗病毒治疗(包括HIV、HBV、EB病毒等)方面的研究,同时也对该系统未来在病毒方面的研究方向进行展望。

     

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  • 收稿日期:  2015-05-07
  • 刊出日期:  2016-01-20
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