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全身化疗联合经肝动脉化疗栓塞术治疗乳腺癌肝转移的疗效观察

李立业

李立业. 全身化疗联合经肝动脉化疗栓塞术治疗乳腺癌肝转移的疗效观察[J]. 临床肝胆病杂志, 2016, 32(1): 97-100. DOI: 10.3969/j.issn.1001-5256.2016.01.017
引用本文: 李立业. 全身化疗联合经肝动脉化疗栓塞术治疗乳腺癌肝转移的疗效观察[J]. 临床肝胆病杂志, 2016, 32(1): 97-100. DOI: 10.3969/j.issn.1001-5256.2016.01.017
Li LiYe. Clinical effect of systemic chemotherapy combined with transcatheter arterial chemoembolization in treatment of breast cancer with liver metastases[J]. J Clin Hepatol, 2016, 32(1): 97-100. DOI: 10.3969/j.issn.1001-5256.2016.01.017
Citation: Li LiYe. Clinical effect of systemic chemotherapy combined with transcatheter arterial chemoembolization in treatment of breast cancer with liver metastases[J]. J Clin Hepatol, 2016, 32(1): 97-100. DOI: 10.3969/j.issn.1001-5256.2016.01.017

全身化疗联合经肝动脉化疗栓塞术治疗乳腺癌肝转移的疗效观察

DOI: 10.3969/j.issn.1001-5256.2016.01.017
详细信息
  • 中图分类号: R737.9

Clinical effect of systemic chemotherapy combined with transcatheter arterial chemoembolization in treatment of breast cancer with liver metastases

  • 摘要:

    目的探讨发生肝转移的乳腺癌患者采用全身化疗联合经肝动脉化疗栓塞术(TACE)治疗的效果。方法选取2012年12月-2014年12月于山东省医学科学院附属医院接受治疗的乳腺癌并发肝转移女性患者86例,将其平均分为试验组和对照组。对照组采用全身化疗,试验组给予全身化疗基础上联合TACE治疗,比较2组临床疗效、病灶变化情况以及治疗后患者生活质量评分情况。计量资料组间比较采用t检验,计数资料组间比较采用χ2检验。结果试验组患者治疗的总有效率高于对照组,差异有统计学意义(90.70%vs 58.14%,χ2=13.07,P=0.001);与对照组相比,试验组患者治疗后肿瘤直径、淋巴结直径较小,差异均有统计学意义(t值分别为4.26、4.63,P值均<0.001);试验组患者治疗后3、6个月生活质量评分均高于对照组,差异均有统计学意义(t值分别为6.30、3.89,P值均<0.001)。结论对乳腺癌肝转移患者采用全身化疗联合TACE治疗的效果显著,能够改善患者症状,减少药物不良反应,提高生活质量,且安全可靠,值得推广应用。

     

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  • 收稿日期:  2015-09-02
  • 刊出日期:  2016-01-20
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