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枯草杆菌二联活菌肠溶胶囊防治经肝动脉化疗栓塞术后不良反应及并发症的效果评价

赵广生 任志忠 刘影 周军 张跃伟 张明

赵广生, 任志忠, 刘影, 周军, 张跃伟, 张明. 枯草杆菌二联活菌肠溶胶囊防治经肝动脉化疗栓塞术后不良反应及并发症的效果评价[J]. 临床肝胆病杂志, 2016, 32(1): 88-91. DOI: 10.3969/j.issn.1001-5256.2016.01.015
引用本文: 赵广生, 任志忠, 刘影, 周军, 张跃伟, 张明. 枯草杆菌二联活菌肠溶胶囊防治经肝动脉化疗栓塞术后不良反应及并发症的效果评价[J]. 临床肝胆病杂志, 2016, 32(1): 88-91. DOI: 10.3969/j.issn.1001-5256.2016.01.015
Zhao GuangSheng, Ren ZhiZhong, Liu Ying, Zhou Jun, Zhang YueWei, Zhang Ming. Effect of live combined Bacillus subtilis and Enterococcus faecium enteric-coated capsules in treatment of adverse events and complications after transcatheter arterial chemoembolization[J]. J Clin Hepatol, 2016, 32(1): 88-91. DOI: 10.3969/j.issn.1001-5256.2016.01.015
Citation: Zhao GuangSheng, Ren ZhiZhong, Liu Ying, Zhou Jun, Zhang YueWei, Zhang Ming. Effect of live combined Bacillus subtilis and Enterococcus faecium enteric-coated capsules in treatment of adverse events and complications after transcatheter arterial chemoembolization[J]. J Clin Hepatol, 2016, 32(1): 88-91. DOI: 10.3969/j.issn.1001-5256.2016.01.015

枯草杆菌二联活菌肠溶胶囊防治经肝动脉化疗栓塞术后不良反应及并发症的效果评价

DOI: 10.3969/j.issn.1001-5256.2016.01.015
详细信息
  • 中图分类号: R735.7

Effect of live combined Bacillus subtilis and Enterococcus faecium enteric-coated capsules in treatment of adverse events and complications after transcatheter arterial chemoembolization

  • 摘要:

    目的探讨枯草杆菌二联活菌肠溶胶囊对经肝动脉化疗栓塞术(TACE)术后不良反应及并发症的防治作用。方法选取2012年1月-2013年12月大连大学附属中山医院收治的择期进行TACE的肝细胞癌患者239例,随机分为试验组(n=111)与对照组(n=128)。其中试验组于术前3 d给予口服枯草杆菌二联活菌肠溶胶囊,对照组服用外形相同的安慰剂,比较2组TACE术后不良反应、并发症发生率及血氨水平。计量资料组间比较采用独立样本t检验,计数资料组间比较采用χ2检验。结果试验组患者发热、腹胀、便秘等不良反应发生率显著低于对照组,差异均有统计学意义(t值分别为2.728、2.561、2.026,P值均<0.05);试验组患者肝脓肿、肠梗阻、自发性腹膜炎、肝性脑病等术后并发症的发生率亦显著低于对照组,差异均有统计学意义(t值分别为1.969、2.312、2.987、2.826,P值均<0.05);经治疗后,与对照组相比,试验组患者血氨水平较低,差异具有统计学意义(t=1.97,P<0.05)。结论枯草杆菌二联活菌肠溶胶囊作为新型活菌制剂,能够降低TACE术后患者腹部不适及血氨水平,并能...

     

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  • 收稿日期:  2015-05-06
  • 刊出日期:  2016-01-20
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