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经肝动脉化疗栓塞术治疗肝细胞癌合并门静脉癌栓的预后影响因素分析

张成 祁兴顺 柏明 赵艳 王维娟 韩国宏

张成, 祁兴顺, 柏明, 赵艳, 王维娟, 韩国宏. 经肝动脉化疗栓塞术治疗肝细胞癌合并门静脉癌栓的预后影响因素分析[J]. 临床肝胆病杂志, 2016, 32(1): 84-87. DOI: 10.3969/j.issn.1001-5256.2016.01.014
引用本文: 张成, 祁兴顺, 柏明, 赵艳, 王维娟, 韩国宏. 经肝动脉化疗栓塞术治疗肝细胞癌合并门静脉癌栓的预后影响因素分析[J]. 临床肝胆病杂志, 2016, 32(1): 84-87. DOI: 10.3969/j.issn.1001-5256.2016.01.014
Zhang Cheng, Qi XingShun, Bo Ming, Zhao Yan, Wang WeiJuan, Han GuoHong. Prognostic factors for transcatheter arterial chemoembolization in patients with hepatocellular carcinoma complicated by portal vein tumor thrombus[J]. J Clin Hepatol, 2016, 32(1): 84-87. DOI: 10.3969/j.issn.1001-5256.2016.01.014
Citation: Zhang Cheng, Qi XingShun, Bo Ming, Zhao Yan, Wang WeiJuan, Han GuoHong. Prognostic factors for transcatheter arterial chemoembolization in patients with hepatocellular carcinoma complicated by portal vein tumor thrombus[J]. J Clin Hepatol, 2016, 32(1): 84-87. DOI: 10.3969/j.issn.1001-5256.2016.01.014

经肝动脉化疗栓塞术治疗肝细胞癌合并门静脉癌栓的预后影响因素分析

DOI: 10.3969/j.issn.1001-5256.2016.01.014
详细信息
  • 中图分类号: R735.7

Prognostic factors for transcatheter arterial chemoembolization in patients with hepatocellular carcinoma complicated by portal vein tumor thrombus

  • 摘要:

    目的评估肝细胞癌(HCC)合并门静脉癌栓患者经肝动脉化疗栓塞术(TACE)治疗后的效果及影响预后的因素。方法回顾性分析2006年1月-2010年12月第四军医大学西京医院收治的152例行TACE治疗的HCC合并门静脉癌栓患者的临床资料。观察TACE术后肝衰竭、上消化道大出血、栓塞后综合征等发生情况,分析生存期资料与影响预后的因素。Kaplan-Meier法计算累积生存率,采用Log-Rank法进行单因素分析,Cox比例风险模型进行多因素分析。结果患者中位生存时间为5.0(95%可信区间:4.45.6)个月,6、12、18个月的累积生存率分别为37%、18%和9%。单因素分析显示肿瘤大小、肿瘤类型、肝两叶累及、远处转移和Child-Pugh分级是HCC合并门静脉癌栓患者行TACE治疗预后的影响因素(χ2值分别为5.108、11.542、6.036、12.319、22.574,P值均<0.05);多因素分析显示肿瘤大小、肿瘤类型、远处转移和Child-Pugh分级是影响患者预后的独立危险因素(Wald值分别为11.243、5.021、7.651、25.876,P...

     

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出版历程
  • 收稿日期:  2015-10-21
  • 刊出日期:  2016-01-20
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