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Acute-on-chronic liver failure due to bacterial infection in liver cirrhosis: causes and management
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摘要:
细菌感染是肝硬化患者常见的合并症,因细菌感染而导致的慢加急性肝衰竭日益成为临床上的突出问题。目前有关肝硬化细菌感染发病机制及其防治策略的研究仍面临许多问题如起病较为隐匿、早期诊断困难、多重耐药菌不断增加等。简要探讨了肝硬化细菌感染的原因和防治措施两个方面的最新进展。未来需要构建更有效的预防、早期诊断、合理治疗的综合防治策略,从而进一步降低重症患者的病死率。
Abstract:Bacterial infection is a common complication in patients with liver cirrhosis,and acute-on-chronic liver failure due to bacterial infection has become a serious clinical problem. There are still many problems in the research on the pathogenesis and management of bacterial infection in liver cirrhosis,such as insidious onset,difficult early diagnosis,and increased multi-drug resistant bacteria. This article reviews the research progress in the causes and management of bacterial infection in liver cirrhosis. More effective strategies for the prevention,early diagnosis,and reasonable treatment of bacterial infection in liver cirrhosis should be developed to reduce the mortality of severe patients.
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Key words:
- liver cirrhosis /
- bacteria infection
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