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The clinical value of D-dimer in cirrhotic patients with portal venous thrombosis
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摘要: 目的探讨D-二聚体在肝硬化门静脉血栓形成中的预测价值。方法选我院自2005年1月至2008年12月所收肝硬化剔除不符合标准者共有83例入组,据螺旋CT增强扫描是否合并PVT分为血栓组和对照组,观测其D-二聚体水平。结果血栓组D-二聚体水平显著高于对照组。结论 D-二聚体水平异常升高可提示门静脉血栓的形成。
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关键词:
- 肝硬化 /
- 门静脉血栓形成 /
- 门静脉 /
- 纤维蛋白纤维蛋白原降解物
Abstract: Objective To evaluate the level of D-dimer as a predictive indicator of portal vein thrombosis (PVT) in liver cirrhosis patients.Methods A total of 83 liver cirrhosis patients were studied prospectively. A change in the level of D-dimer was analyzed.Results The level of D-dimer in PVT patients was significantly higher than the non-PVT patients. The possibility of PVT increased with the increase in D-dimer level.Conclusion Active monitoring of D-dimer levels in patients with portal hypertension could help in early diagnosis of PVT. -
[1]Fimoqnari FL, Violi F.Portal vein thrombosis in liver cirrhosis[J].Intern Emerq Med, 2008, 3 (3) ∶213-218. [2]Amitrano L, Guardascione MA, Ames PR.Coagulation abnormalities in cirrhotic patients with portal vein thrombosis[J].Clin Lab, 2007, 53 (9-12) ∶583-589. [3]Mangia A, Villani MR, Cappucci G, et al.Causes of portal venous thrombosis in cirrhotic patients:the role of genetic and acquired fac-tors[J].Eur J Gastroenterol Hepatol, 2005, 17 (7) ∶745-751. [4]张冬磊, 杨宁.肝硬化患者门静脉血栓形成的相关危险因素[J].世界华人消化杂志, 2008, 16 (27) ∶3105-3109. [5]Deng MH, LIUB, Fang HP, et al.Predictive value of D-dimer for portal vein thrombosis after portal hypertension surgery in hepatitis B virus-related cirrhosis[J].Word J Gastroenterol, 2007, 13 (48) ∶6588-6592. -
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