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ISSN 1001-5256 (Print)
ISSN 2097-3497 (Online)
CN 22-1108/R
Issue 1
Jan.  2012
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Surgical treatment of rectal cancer with synchronous hepatic metastases

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  • Published Date: 2012-01-20
  • Objective To investigate the surgical occasion and approach of rectal cancer with synchronous hepatic metastases.Methods Retrospective analysis was conducted on the clinical data of 32 patients who had been diagnosed as rectal cancer with synchronous hepatic metastases.Results The resectability of hepatic metastasis site from rectal cancer for the patient could be exactly diagnosed by type-B ultrasonic, computer tomography (CT) and magnetic resonance imaging (MRI) before surgical operation.Neo-adjuvant chemotherapy and targeted therapy would aid a lot in the further filter of patients who had been diagnosed as rectal cancer with synchronous hepatic metastases.Comprehensive therapy which mainly based on surgical was adopted.Conclusion Surgical treatment was still the first choice for the patients with resectable rectal cancer with synchronous hepatic metastases.Appropriate subject-specific comprehensive therapy could improve the disease free survival rate and accumulated survival rate.

     

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  • [1]Sadahiro S, Suzuki T, Ishikawa K, et al.Recurrence patternsafter curative resection of colorectal cancer in patients fol-lowed for a minimum of ten years[J].Hepatogastroenterol-ogy, 2003, 50 (53) :1362-1366.
    [2]Bentrem DJ, Dematteo RP.Blumgart LH.Surgical therapyfor metastatic disease to the liver[J].Annu RevMed, 2005, 56:139-156.
    [3]Morris EJ, Forman D, Thomas JD, et al.Surgical manage-ment and outcomes of colorectal cancer liver metastases[J].Br J Surg, 2010, 97 (7) :1110-1118.
    [4]Ito K, Govindarajan A, Ito H, et al.Surgical treatment of he-patic colorectal metastasis:evolving role in the setting of im-proving systemic therapies and ablative treatments in the21st century[J].Cancer J, 2010, 16 (2) :103-110.
    [5]Tsim NC, Frampton AE, Habib NA, et al.Surgical treatmentfor liver cancer[J].World J Gastroenterol, 2010, 16 (8) :927-933.
    [6]许剑民, 钟芸诗, 秦新裕.同时性结直肠癌肝转移的外科治疗进展[J].中华普外科手术学杂志:电子版, 2010, 4 (1) :10-15.
    [7]NCCN Clinical Practice Guidelines in Oncology (NCCN Guide-linesTM) .Colon Cancer.Version 3.2011.http://www.neen.org/professionals/physiciangls/pdf/colon.pdf.
    [8]Nordlinger B, Van Cutsem E, Gruenberger T, et al.Europe-an colorectal metastases treatment group, sixth internationalcolorectal liver metastases workshop.combination of surgeryand chemotherapy and the role of targete dagents in thetreatment of patients with colorectal liver metastases:recom-mendaions from an expertpanel[J].Ann Oncol, 2009, 20 (6) :985-992.
    [9]Sugihara K, Kobayashi H, Kato T, et al.Indication and bene-fit of pelvic sidewall dissection for rectal Cancer[J].Dis Co-lon Rectum, 2006, 49 (11) :1663-1672.
    [10]Dong XS, Xu HT, Yu ZW, et al.Effect of extended radicalresection for rectal cancer[J].World J Gastroenterol, 2003, 9 (5) :970-973.
    [11]Liang JT, Lai HS, Lee PH.Laparoscopic pelvic autonomicnerve-preserving surgery for patients with lower rectalCancer after chemoradiation therapy[J].Ann Surg Oncol, 2007, 14 (4) :1285-1287.
    [12]邢宝才, 丁兆武.结直肠癌肝转移的术前化疗[J].中国普外基础与临床杂志, 2011, 18 (5) :473-474.
    [13]Verhoef C, van der Pool AE, Nuyttens JJ, et al.The“liver-first approach”for patients with locally advanced rectal Canc-er and synchronous liver metastases[J].Dis Colon Rectum, 2009, 52 (1) :23-30.
    [14]倪俊生, 周伟平.结直肠癌肝转移的外科治疗策略[J].肝胆外科杂志, 2011, 19 (1) :67-69.
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