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Volume 40 Issue 7
Jul.  2024
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Article Navigation >  Journal of Clinical Hepatology  > 2024  >  40(7): 1289-1294

Treatment of metastatic liver cancer： Current status and future perspectives

DOI: 10.12449/JCH240701

  • Center of Hepatobiliary Surgery，Department of General Surgery，Huashan Hospital，Fudan University，Shanghai 200040，China

Research funding:

Excellent Academic Leader Project of Shanghai “Science and Technology Innovation Action Plan” (22XD1400300)

More Information
  • Corresponding author: CHEN Jinhong， jinhongch@hotmail.com （ORCID： 0000-0003-0952-9990）
  • Received Date: 2024-04-22
  • Accepted Date: 2024-05-17
  • Published Date: 2024-07-25
    Abstract
  • The liver is a common metastatic site of malignant tumors， and liver metastasis is also the leading cause of death due to metastatic tumors. Metastatic liver cancer has high heterogeneity， and there has been slow progress in the treatment of metastatic liver cancer for a long time. In recent years， the development of surgical techniques， systemic therapy， and the multidisciplinary team （MDT） diagnostic and therapeutic mode has led to revolutionary changes in the clinical management of metastatic liver cancer. The article reviews the recent progress in the treatment of metastatic liver cancer from the three aspects of surgical treatment， systemic therapy， and locoregional therapy. Combined therapy based on chemotherapy， targeted therapy， and immunotherapy remains the basic multimodality therapy for metastatic liver cancer. In addition， the development of locoregional therapy has brought new treatment options for patients with metastatic liver cancer. Standardized diagnosis and treatment based on high-level evidence-based evidence and related guidelines and individualized precise treatment under the guidance of MDT will be the future directions for the clinical management of metastatic liver cancer.

     

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