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ISSN 1001-5256 (Print)
ISSN 2097-3497 (Online)
CN 22-1108/R
Volume 37 Issue 7
Jul.  2021
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Article Navigation >  Journal of Clinical Hepatology  > 2021  >  37(7): 1648-1651

Value of contrast-enhanced endoscopic ultrasound versus contrast-enhanced computed tomography in the diagnosis of pancreatic solid space-occupying lesions

DOI: 10.3969/j.issn.1001-5256.2021.07.033

  • Department of Gastroenterology, Beijing Tiantan Hospital, Capital Medical University, Beijing 100070, China

Research funding:

Capital Research Funds for Medical Development (Capital Development 2020-1-2042)

  • Received Date: 2020-12-05
  • Accepted Date: 2021-01-21
  • Published Date: 2021-07-20
    Abstract
  •   Objective  To investigate the value of contrast-enhanced endoscopic ultrasound (CE-EUS) versus contrast-enhanced computed tomography (CE-CT) in the diagnosis of pancreatic solid space-occupying lesions.  Methods  A total of 78 patients with pancreatic solid space-occupying lesions who attended Beijing Tiantan Hospital, Capital Medical University, from January 2014 to December 2019 were enrolled. All patients were diagnosed by EUS-guided fine needle aspiration or postoperative pathology, and CE-EUS and CE-CT were compared in terms of their accuracy, sensitivity, specificity, and Youden index in the diagnosis of pancreatic solid space-occupying lesions.  Results  In the diagnosis of pancreatic cancer, CE-EUS and CE-CT had accuracy rates of 97.9% and 87.2%, sensitivities of 97.7% and 88.9%, specificities of 100% and 50%, and Youden indices of 0.96 and 0.76, respectively. In the diagnosis of small pancreatic cancer, CE-EUS and CE-CT had accuracy rates of 84.6% and 61.5%, sensitivities of 80% and 70%, specificities of 100% and 33.3%, and Youden indices of 0.80 and 0.03, respectively. In the diagnosis of chronic pancreatitis with mass, CE-EUS and CE-CT had accuracy rates of 90.5% and 61.9%, sensitivities of 94.1% and 64.7%, specificities of 75% and 50%, and Youden indices of 0.69 and 0.15, respectively. In the diagnosis of pancreatic neuroendocrine tumors, CE-EUS and CE-CT had accuracy rates of 85.7% and 28.6%, sensitivities of 83.3% and 16.7%, specificities of 100% and 100%, and Youden indices of 0.83 and 0.17, respectively.  Conclusion  CE-EUS has certain advantages over CE-CT in the diagnosis of pancreatic solid space-occupying lesions.

     

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    • References(14)
  • [1]
    LENNON AM, HRUBAN RH, KLEIN AP. Screening for pancreatic cancer-Is there hope?[J]. JAMA Intern Med, 2019, 179(10): 1313-1315. DOI: 10.1001/jamainternmed.2019.3323.
    [2]
    SIEGEL RL, MILLER KD, JEMAL A. Cancer statistics, 2018[J]. CA Cancer J Clin, 2018, 68(1): 7-30. DOI: 10.3322/caac.21442.
    [3]
    ANAIZI A, HART PA, CONWELL DL. Diagnosing chronic pancreatitis[J]. Dig Dis Sci, 2017, 62(7): 1713-1720. DOI: 10.1007/s10620-017-4493-2.
    [4]
    AZIZIAN A, RVHLMANN F, KRAUSE T, et al. CA19-9 for detecting recurrence of pancreatic cancer[J]. Sci Rep, 2020, 10(1): 1332. DOI: 10.1038/s41598-020-57930-x.
    [5]
    FANG X, BIAN Y, WANG L, et al. Significance and differential diagnosis of pancreatic imaging examination in clinical decision-making[J]. Chin J Dig Surg, 2020, 19(4): 449-454. DOI: 10.3760/cma.j.cn115610-20200409-00241.

    方旭, 边云, 王莉, 等. 胰腺影像学检查在临床决策中的意义及鉴别诊断[J]. 中华消化外科杂志, 2020, 19(4): 449-454. DOI: 10.3760/cma.j.cn115610-20200409-00241.
    [6]
    SRISAJJAKUL S, PRAPAISILP P, BANGCHOKDEE S. CT and MR features that can help to differentiate between focal chronic pancreatitis and pancreatic cancer[J]. Radiol Med, 2020, 125(4): 356-364. DOI: 10.1007/s11547-019-01132-7.
    [7]
    STORM AC, LEE LS. Endoscopic ultrasound-guided techniques for diagnosing pancreatic mass lesions: Can we do better?[J]. World J Gastroenterol, 2016, 22(39): 8658-8669. DOI: 10.3748/wjg.v22.i39.8658.
    [8]
    CAI BB, GAO Y, WANG GP, et al. Advances in diagnosis and treatment of pancreatic diseases of the Nanjing Pancreas Forum 2018[J]. Chin J Dig Surg, 2019, 18(1): Ⅲ-Ⅶ. DOI: 10.3760/cma.j.issn.1673-9752.2019.01.101.

    蔡宝宝, 杲勇, 王广甫, 等. Nanjing Pancreas Forum 2018: 胰腺疾病诊断与治疗进展解析[J]. 中华消化外科杂志, 2019, 18(1) : Ⅲ-Ⅶ. DOI: 10.3760/cma.j.issn.1673-9752.2019.01.101.
    [9]
    KITANO M, YOSHIDA T, ITONAGA M, et al. Impact of endoscopic ultrasonography on diagnosis of pancreatic cancer[J]. J Gastroenterol, 2019, 54(1): 19-32. DOI: 10.1007/s00535-018-1519-2.
    [10]
    LI Y, JIN H, LIAO D, et al. Contrast-enhanced harmonic endoscopic ultrasonography for the differential diagnosis of pancreatic masses: A systematic review and meta-analysis[J]. Mol Clin Oncol, 2019, 11(4): 425-433. DOI: 10.3892/mco.2019.1908.
    [11]
    MEI S, WANG M, SUN L. Contrast-enhanced EUS for differential diagnosis of pancreatic masses: A meta-analysis[J]. Gastroenterol Res Pract, 2019, 2019: 1670183. DOI: 10.1155/2019/1670183.
    [12]
    PULEO F, MARÉCHAL R, DEMETTER P, et al. New challenges in perioperative management of pancreatic cancer[J]. World J Gastroenterol, 2015, 21(8): 2281-2293. DOI: 10.3748/wjg.v21.i8.2281.
    [13]
    OKUSAKA T, NAKAMURA M, YOSHIDA M, et al. Clinical practice guidelines for pancreatic cancer 2019 from the Japan Pancreas Society: A synopsis[J]. Pancreas, 2020, 49(3): 326-335. DOI: 10.1097/MPA.0000000000001513.
    [14]
    LI XZ, SONG J, SUN ZX, et al. Diagnostic performance of contrast-enhanced ultrasound for pancreatic neoplasms: A systematic review and meta-analysis[J]. Dig Liver Dis, 2018, 50(2): 132-138. DOI: 10.1016/j.dld.2017.10.012.
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