Clinical diagnosis of drug-induced autoimmune-like hepatitis

Yongping LIU; Yaojie SHEN

doi:10.12449/JCH250322

Volume 41 Issue 3

Mar. 2025

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Article Navigation > Journal of Clinical Hepatology > 2025 > 41(3): 542-546

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Clinical diagnosis of drug-induced autoimmune-like hepatitis

DOI: 10.12449/JCH250322

Yongping LIU¹,
Yaojie SHEN^{2
,
,
,}

1.
Department of Hepatology，Hangzhou Xixi Hospital Affiliated to Zhejiang University of Chinese Medicine，Hangzhou 310023，China
2.
Clinical Experiment Center，Zhejiang Hospital of Integrated Traditional Chinese and Western Medicine，Hangzhou 310003，China

Research funding:

Medical Health Science and Technology Project of Zhejiang Provincial Health Commission (2024KY212);

Hangzhou Biomedicine and Health Industry Development Support Science and Technology Special Project (2022WJC283)

More Information

Corresponding author: SHEN Yaojie， shenyaojie2024@163.com （ORCID： 0000-0003-3081-9597）
Received Date: 2024-05-31
Accepted Date: 2024-07-26
Published Date: 2025-03-25

Abstract

Abstract

Some patients with drug-induced liver injury （DILI） may present with similar features to patients with autoimmune hepatitis （AIH）， and such cases are defined as drug-induced autoimmune-like hepatitis （DI-ALH）. In 2022， the European Association for the Study of the Liver discussed the nomenclature， diagnosis， and treatment of DI-ALH and put forward expert opinions to establish the criteria for clinical diagnosis. However， the clinical diagnosis of DI-ALH remains complex and difficult， and there is no direct evidence for the link between drug intake and the body’s immune progression. Therefore， this article reviews the research advances in the diagnosis of DI-ALH from the four aspects of clinical phenotype， pathological diagnosis， diagnostic score， and clinical prognosis.
- Drug-induced Autoimmune-like Hepatitis,
- Drug-induced Liver Injury,
- Hepatitis， Autoimmune,
- Diagnosis

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References(43)

References

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Clinical diagnosis of drug-induced autoimmune-like hepatitis

DOI: 10.12449/JCH250322

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Clinical diagnosis of drug-induced autoimmune-like hepatitis

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