Role of extracellular vesicles of different origins in the development and progression of hepatocellular carcinoma

Tingting SHI; Runbing ZHANG; Yang WU; Yani ZHANG; Lingling ZHU; Chun GAO; Jingjing JIANG; Xiaofeng ZHENG; Jiucong ZHANG

doi:10.12449/JCH240630

Volume 40 Issue 6

Jun. 2024

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Article Navigation > Journal of Clinical Hepatology > 2024 > 40(6): 1264-1268

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Role of extracellular vesicles of different origins in the development and progression of hepatocellular carcinoma

DOI: 10.12449/JCH240630

Tingting SHI^{1, 2},
Runbing ZHANG^{1, 2},
Yang WU^{1, 2},
Yani ZHANG^{1, 2},
Lingling ZHU^{1, 2},
Chun GAO^{1, 2},
Jingjing JIANG^{1, 2},
Xiaofeng ZHENG^{3
,
,
,},
Jiucong ZHANG^{1
,
,
,}

1.
Department of Gastroenterology，The 940 Hospital of Joint Logistic Support Force of PLA，Lanzhou 730050，China
2.
The First Clinical Medical College of Gansu University of Chinese Medicine，Lanzhou 730000，China
3.
Department of Gastroenterology，The Second Hospital of Lanzhou University，Lanzhou 730030，China

Research funding:

Central University Excellent Youth Team Cultivation Project (31920220065);

Gansu Clinical Medical Research Center for Non-infectious Liver Diseases (21JR7RA017);

Gansu Natural Science Foundation (22JR5RA1012);

Lanzhou Youth Science and Technology Talent Innovation Key Project (2023-2-29);

Gansu Youth Science and Technology Fund (23JRRA1673)

More Information

Corresponding author: ZHENG Xiaofeng， zhengxf19892013@126.com （ORCID： 0009-0002-9660-1224）; ZHANG Jiucong， zhangjiucong@163.com （ORCID： 0000-0003-4006-3033）
Received Date: 2024-01-09
Accepted Date: 2024-02-01
Published Date: 2024-06-25

Abstract

Abstract

Hepatocellular carcinoma （HCC） is the most common type of primary liver cancer and the third leading cause of cancer-related deaths， and it is a serious threat to human health and has become a clinical problem that needs to be solved urgently. Extracellular vesicles （EV） are membrane vesicles containing multiple components and play an important role in the development and progression of HCC. This article summarizes the effect of EVs of different origins on HCC and analyzes the mechanism of action of EV on HCC， so as to provide new perspectives for the diagnosis and treatment of HCC.
- Carcinoma， Hepatocellular,
- Extracellular Vesicles,
- Diagnosis

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References(34)

References

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